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首页> 外文期刊>Journal of the American Society of Nephrology: JASN >Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN
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Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN

机译：梅奥诊所/肾脏病理学会关于GN的病理学分类，诊断和报告的共识报告

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Renal pathologists and nephrologists met on February 20, 2015 to establish an etiology/pathogenesis-based system for classification and diagnosis of GN, with a major aim of standardizing the kidney biopsy report of GN. On the basis of etiology/pathogenesis, GN is classified into the following five pathogenic types, each with specific disease entities: immune-complex GN, pauci-immune GN, antiglomerular basement membrane GN, monoclonal Ig GN, and C3 glomerulopathy. The pathogenesis based classification forms the basis of the kidney biopsy report. To standardize the report, the diagnosis consists of a primary diagnosis and a secondary diagnosis. The primary diagnosis should include the disease entity/pathogenic type (if disease entity is not known) followed in order by pattern of injury (mixed patterns may be present); score/grade/class for disease entities, such as IgA nephropathy, lupus nephritis, and ANCA GN; and additional features as detailed herein. A pattern diagnosis as the sole primary diagnosis is not recommended. Secondary diagnoses should be reported separately and include coexisting lesions that do not form the primary diagnosis. Guidelines for the report format, light microscopy, immunofluorescence microscopy, electron microscopy, and ancillary studies are also provided. In summary, this consensus report emphasizes a pathogenesis-based classification of GN and provides guidelines for the standardized reporting of GN.
机译：肾脏病理学家和肾脏病学家于2015年2月20日开会，建立了基于病因/发病机制的GN分类和诊断系统，其主要目的是标准化GN肾活检报告。根据病因/发病机制，GN被分为以下五种致病类型，每种具有特定的疾病实体：免疫复合物GN，弱免疫性GN，抗肾小球基底膜GN，单克隆Ig GN和C3肾小球病。基于发病机制的分类构成了肾脏活检报告的基础。为了使报告标准化，诊断包括主要诊断和辅助诊断。主要诊断应包括疾病实体/致病类型（如果未知疾病实体），其后依次是伤害模式（可能存在混合模式）;疾病实体（例如IgA肾病，狼疮性肾炎和ANCA GN）的得分/等级/类别;以及此处详细介绍的其他功能。不建议将模式诊断作为唯一的主要诊断。二级诊断应单独报告，包括不构成初级诊断的共存病变。还提供了报告格式，光学显微镜，免疫荧光显微镜，电子显微镜和辅助研究的指南。总之，这份共识报告强调了基于发病机理的GN分类，并为GN的标准化报告提供了指导。

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