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EEG and the variance of motor evoked potential amplitude.

机译:脑电图和电机诱发电位振幅的方差。

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摘要

The motor threshold is an important parameter in selecting the treatment intensity of patients undergoing transcranial magnetic stimulation. The large variance in magnitude of motor evoked responses has forced clinicians to perform many trials and average the results to find a repeatable value for motor threshold. Our objective is to investigate the source of the variance in amplitude. Four clinically healthy adult males participated in an EEG and EMG during transcranial magnetic stimulation of the left motor cortex, 100% motor threshold, 0.1 Hz. Per our hypothesis, a significant negative correlation of .22 was found between the amplitude of the motor evoked potential and the power in the high alpha frequency band during the pre-stimulus period (p < .001). In addition, a significant positive correlation of .17 was found between the motor evoked potential (MEP) amplitude and the gamma band (p < .001). The strongest correlation of .27 (p < .001) was found between the MEP amplitude and the ratio of the power in the low gamma to high alpha band. We conclude that the gamma to alpha power ratio may be a useful indicator of cortical excitability.
机译:运动阈值是选择接受经颅磁刺激的患者的治疗强度的重要参数。运动诱发反应幅度的巨大差异迫使临床医生进行许多试验,并对结果求平均值,以找到可重复的运动阈值。我们的目标是研究幅度变化的来源。四名临床健康的成年男性在经颅磁刺激左运动皮层,100%运动阈值,0.1 Hz时参与了EEG和EMG。根据我们的假设,在激励前的周期中,电机诱发电位的幅度与高α频段的功率之间存在显着的.22负相关(p <.001)。此外,在电机诱发电位(MEP)幅度和伽马谱带之间发现.17的显着正相关(p <.001)。在MEP振幅与低伽玛与高α波段的功率之比之间发现了.27的最强相关性(p <.001)。我们得出结论,伽马与阿尔法功率比可能是皮质兴奋性的有用指标。

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