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首页> 外文期刊>Journal of the American Academy of Child and Adolescent Psychiatry >Open trial of family-based treatment for full and partial anorexia nervosa in adolescence: evidence of successful dissemination.
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Open trial of family-based treatment for full and partial anorexia nervosa in adolescence: evidence of successful dissemination.

机译：青春期完全和部分神经性厌食症的家庭治疗开放试验：成功传播的证据。

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OBJECTIVE: There is a paucity of evidence-based interventions for anorexia nervosa (AN). An innovative family-based treatment (FBT), developed at the Maudsley Hospital and recently put in manual form, has shown great promise for adolescents with AN. Unlike traditional treatment approaches, which promote sustained autonomy around food, FBT temporarily places the parents in charge of weight restoration. This aim of this open trial was to investigate the feasibility and effectiveness of delivering FBT at a site beyond the treatment's origin and manualization. METHOD: Twenty adolescents (ages 12-17) with AN or subthreshold AN were treated with up to 1 year of FBT using the published treatment manual. Outcome indices included the percentage of ideal body weight, menstrual status, the Eating Disorder Examination (EDE) subscales scores, and the Children's Depression Rating Scale-Revised score. RESULTS: Of the 20 patients recruited, 15 (75%) completed a full course of treatment. Intent-to-treat analyses showedsignificant improvement over time in the percentage of ideal body weight (t = -4.46, p =.000), menstrual status (p =.002), EDE Restraint (z -3.02, p Shape Concern or Weight Concern subscales or Children's Depression Rating Scale-Revised score. CONCLUSIONS: This open trial provides evidence that FBT can be successfully disseminated, replicating the high retention rates and significant improvement in the psychopathology of adolescent AN seen at the original sites.
机译：目的：缺乏基于证据的神经性厌食症（AN）干预措施。由Maudsley医院开发的一种创新的基于家庭的治疗（FBT），最近以手动形式投入使用，它为患有AN的青少年显示了巨大的希望。与传统的治疗方法促进食物的持续自治不同，FBT暂时让父母负责体重恢复。这项公开试验的目的是研究在治疗来源和人工之外的地方进行FBT的可行性和有效性。方法：使用出版的治疗手册，对20名年龄在12岁至17岁之间的AN或亚阈值AN的青少年进行长达1年的FBT治疗。结果指标包括理想体重百分比，月经状况，饮食失调考试（EDE）子量表分数和“儿童抑郁量表”修订分数。结果：在招募的20名患者中，有15名（75％）完成了整个疗程。意向性治疗分析显示，理想体重百分比（t = -4.46，p = .000），月经状态（p = .002），EDE约束（z -3.02，p形状关注或体重）随时间显着改善结论：这项公开试验提供了可以成功传播FBT的证据，可以复制FBT的高保留率，并可以改善在原位观察到的青少年AN的心理病理状况。

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