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The Genus Streptococcus: Part I: Emerging Pathogens in the “Pyogenic Cocci” and the “Streptococcus bovis” Groups

机译:链球菌属:第一部分:“化脓性球菌”和“牛链球菌”组中的新兴病原体

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In this first part of a two-part update on the streptococci, new and emerging pathogens in the “pyogenic cocci group” and the “Streptococcus bovis group” are addressed. Among the pyogenic cocci, several new species have been described, and some of these are becoming relevant agents of human disease. Streptococcus porcinus and Streptococcus pseudoporcinus are β-hemolytic streptococci that are found in swine and humans, respectively. S. pseudoporcinus has been isolated primarily from the female genital tract and may play a role in genitourinary tract infections, wound infections, and adverse pregnancy outcomes. Streptococcus iniae, Streptococcus hongkongensis, and Streptococcus ictaluri are fish pathogens, and S. iniae, in particular, has been isolated from several human infections in persons who handle raw seafood or experience penetrating injuries from fish spines or crab pincers. Streptococcus gallolyticus subspecies (i.e., the former “S. bovis group”) are well-recognized causes of bacteremia, meningitis, and endocarditis. S. gallolyticus subsp. gallolyticus is known to be associated with colon cancer, and current studies suggest that other S. gallolyticus subspecies (particularly S. gallolyticus subsp. pasteurianus) may also be associated with meningitis and other digestive tract malignancies. In this review, current research on S. gallolyticus subspecies and proposed mechanisms for their involvement in the pathogenesis of colonic carcinoma are also briefly addressed.
机译:在有关链球菌的两部分更新的第一部分中,讨论了“化脓性球菌组”和“牛链球菌”组中新出现的病原体。化脓性球菌中,已经描述了几种新物种,其中一些正在成为人类疾病的相关病原体。猪链球菌和伪猪链球菌是分别在猪和人体内发现的β-溶血性链球菌。伪猪链球菌主要从女性生殖道中分离出来,可能在泌尿生殖道感染,伤口感染和不良妊娠结局中起作用。病链球菌,香港链球菌和尼卡链球菌是鱼类病原体,尤其是在处理生海鲜或遭受鱼刺或蟹钳刺伤的人的几种人类感染中已分离出尤其是海豚链球菌。溶脂链球菌亚种(即以前的“牛链球菌”)是公认的引起菌血症,脑膜炎和心内膜炎的原因。 S.gallolyticus亚种。已知溶脂蛋白与结肠癌有关,目前的研究表明其他溶脂葡萄球菌亚种(尤其是溶脂葡萄球菌巴氏杆菌亚种)也可能与脑膜炎和其他消化道恶性肿瘤有关。在这篇综述中,还简要介绍了目前有关解鸡链球菌亚种的研究及其所提议的参与结肠癌发病机制的机制。

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