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首页> 外文期刊>Journal of the American Academy of Nurse Practitioners. >A brief review of pharmacotherapeutic treatment options in smoking cessation: bupropion versus varenicline.
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A brief review of pharmacotherapeutic treatment options in smoking cessation: bupropion versus varenicline.

机译：戒烟中的药物治疗选择简要回顾：安非他酮vs伐尼克兰。

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摘要

PURPOSE: The purpose of this article is to compare the efficacy of two prominent medications utilized in smoking cessation: bupropion and varenicline. DATA SOURCES: Comprehensive review of the literature on bupropion and varenicline including randomized control trials, government reports, journal reviews, and pharmaceutical inserts. CONCLUSIONS: In all studies comparing varenicline to bupropion and/or placebo, varenicline yielded a greater cessation rate at both 3 and 12 months. Additionally, varenicline 1 mg indicated an increased potential for long-term cessation success when compared with varenicline 0.5 mg. When compared with only placebo, bupropion demonstrated a higher efficacy for cessation both at 3 and 12 months. IMPLICATIONS FOR PRACTICE: Only 6% of the 20 million smokers who attempt to quit will succeed in long term. Clinicians must assess their patient's willingness to quit and educate them about cessation options. Knowing the efficacy of various treatment options for patients will potentially increase their success at quitting smoking. Understanding the treatment options available, allows for clinicians to provide the best possible method for smoking cessation for their patient population.
机译：目的：本文的目的是比较两种主要的戒烟药物：安非他酮和伐尼克兰的疗效。数据来源：对安非他酮和伐尼克兰文献的全面审查，包括随机对照试验，政府报告，期刊评论和药品说明书。结论：在所有比较伐尼克兰与安非他酮和/或安慰剂的研究中，伐尼克兰在3个月和12个月时戒烟率更高。此外，与0.5 mg缬尼克林相比，1 mg伐尼克兰表明长期戒烟成功的可能性增加。与仅安慰剂相比，安非他酮在3个月和12个月时均显示出更高的戒烟疗效。实践意义：尝试戒烟的2000万烟民中，只有6％能够长期成功。临床医生必须评估患者的戒烟意愿，并对戒烟方案进行教育。了解各种治疗方案对患者的疗效将有可能增加其戒烟的成功率。了解可用的治疗方案，使临床医生可以为其患者群体提供最佳的戒烟方法。

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