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首页> 外文期刊>Journal of the American Academy of Nurse Practitioners. >Prostate-specific antigen screening: A critical review of current research and guidelines
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Prostate-specific antigen screening: A critical review of current research and guidelines

机译：前列腺特异性抗原筛查：对当前研究和指南的严格审查

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Purpose: Screening for prostate cancer (adenocarcinoma of the prostate), using the prostate-specific antigen (PSA) test is controversial among health professionals and organizations who publish screening guideline recommendations for healthcare professionals. Controversy stems from conflicting research studies regarding the efficacy of PSA screening with regard to improved survival rates. This article serves as a critical review of the current guidelines and research to determine which screening practices may be most beneficial to utilize with patients.Data sources: Literature review of evidence for and against using the PSA test as a screening tool published from 2007 to 2012.Conclusions: Some earlier evidence is currently used to support the guideline recommendations published by professional organizations that recommend against routine screening of asymptomatic men. However, the majority of the latest research demonstrates consistent results showing a reduction in mortality associated with PSA screening.Implications for practice: Initiating screening at age 40, to obtain a baseline value, is recommended for primary care providers and is supported by the most recent evidence.
机译：目的：使用前列腺特异性抗原（PSA）测试筛查前列腺癌（前列腺腺癌）在医疗专业人员和为医疗专业人员发布筛查指南建议的组织中引起争议。关于PSA筛查在提高生存率方面的功效的争议研究来自于相互矛盾的研究。本文是对当前指南和研究的批判性审查，以确定哪些筛查实践可能最有利于患者使用数据来源：2007年至2012年间发表的关于使用PSA测试作为筛查工具的证据的反证结论：目前，一些早期证据被用于支持由专业组织发布的指南建议，这些建议反对对无症状男性进行常规筛查。然而，大多数最新研究显示出一致的结果，表明与PSA筛查相关的死亡率降低了。对实践的意义：建议为初级保健提供者在40岁时开始筛查以获得基线值，并得到最新的支持证据。

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