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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >Set-shifting in adults with ADHD
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Set-shifting in adults with ADHD

机译：成人多动症的定型转移

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Difficulties related to inhibition and set-shifting have been suggested as possible endophenotypes of Attention Deficit Hyperactivity Disorder (ADHD). However, such difficulties have not been consistently found in studies using standard neuropsychological tests. This has been partly explained by the complexity of these tests and the need to include contrast measures which control for more basic functions. The purpose of the present study was to examine whether difficulties related to inhibition and set-shifting in adult ADHD patients could be revealed by the Color Word Interference Test (CWIT) from the Delis Kaplan Executive Function System (D-KEFS). A clinically recruited group of adults with ADHD (n = 60) obtained significantly lower scores than population derived controls (n = 60) on both primary summary (p <.001) and contrast measures (p =.004) of set-shifting. The differences between the groups remained statistically significant after controlling for intellectual function and working memory (p =.003). However, no significant differences between the groups were observed on any measure of inhibition. The study indicates that adults with ADHD have specific difficulties with set-shifting as measured by the CWIT, difficulties that probably also reflect problems related to executive function in their daily life.
机译：已经提出了与抑制和组移位有关的困难，作为注意力缺陷多动障碍（ADHD）的可能的内表型。但是，在使用标准神经心理学测试的研究中并未始终发现此类困难。这些测试的复杂性以及需要包括对比措施以控制更多基本功能的部分解释了这一点。本研究的目的是研究通过成人熟食计划执行功能系统（D-KEFS）的颜色词干扰测试（CWIT）是否可以揭示与成人多动症患者抑制和移位有关的困难。经过临床招募的成年人多动症（n = 60）组在主要摘要（p <.001）和对比测量（p = .004）上，得分均低于人群衍生对照组（n = 60）。控制智力功能和工作记忆后，两组之间的差异仍具有统计学意义（p = .003）。然而，在任何抑制措施上均未观察到两组之间的显着差异。这项研究表明，根据CWIT的测量，患有ADHD的成年人在换档方面有特定的困难，这些困难也可能反映了他们日常生活中与执行功能相关的问题。

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