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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >Alerting network dysfunction in early multiple sclerosis
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Alerting network dysfunction in early multiple sclerosis

机译:早期多发性硬化症的警报网络功能障碍

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摘要

The objective of this study is to assess attention in recently diagnosed relapsing-remitting multiple sclerosis patients. Twenty-seven patients with early multiple sclerosis and low clinical disability scores (EDSS<2) and 27 sex-, age-, and education-matched healthy controls underwent attention assessment using the Attentional Network Test, a computerized task designed to measure efficiency independently in 3 attentional networks (Alerting, Orienting and Executive Control). MS patients had significantly less efficiency in the Alerting network (p =.006). In contrast, in the Orienting and Executive Control networks, they did not differ from controls. A significant interaction between Alerting and Executive Control was also found in the MS patients (p =.007). Early relapsing-remitting multiple sclerosis particularly affects the Alerting domain of attention, whereas the Orienting and Executive Control domains are not affected.
机译:这项研究的目的是评估最近诊断为复发缓解型多发性硬化症患者的注意力。 27名患有早期多发性硬化症且临床残疾评分较低(EDSS <2)且有27名性别,年龄和教育水平匹配的健康对照的患者接受了使用注意力网络测试的注意力评估,该网络任务旨在独立地评估患者的效率3个注意网络(警报,定向和执行控制)。 MS患者在Alerting网络中的效率显着降低(p = .006)。相反,在定向和执行控制网络中,它们与控制没有区别。在MS患者中也发现了警戒与执行控制之间的显着相互作用(p = .007)。早期复发缓解型多发性硬化症尤其会影响注意的警戒域,而定向和执行控制域则不受影响。

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