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首页> 外文期刊>Journal of the International Neuropsychological Society: JINS >ACTIVE cognitive training and rates of incident dementia
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ACTIVE cognitive training and rates of incident dementia

机译：主动认知训练和痴呆发生率

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摘要

Systematic cognitive training produces long-term improvement in cognitive function and less difficulty in performing activities of daily living. We examined whether cognitive training was associated with reduced rate of incident dementia. Participants were from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study (n = 2,802). Incident dementia was defined using a combination of interview-and performance-based methods. Survival analysis was used to determine if ACTIVE treatment affected the rate of incident dementia during 5 years of follow-up. A total of 189 participants met criteria for incident dementia. Baseline factors predictive of incident dementia were older age, male gender, African American race, fewer years of education, relationship other than married, no alcohol use, worse MMSE, worse SF-36 physical functioning, higher depressive symptomatology, diabetes, and stroke (all p <.05). A multivariable model with significant predictors of incident dementia and training group revealed that cognitive training was not associated with a lower rate of incident dementia. Cognitive training did not affect rates of incident dementia after 5 years of follow-up. Longer follow-up or enhanced training may be needed to fully explore the preventive capacity of cognitive training in forestalling onset of dementia.
机译：系统的认知训练可长期改善认知功能，并减少日常活动的难度。我们检查了认知训练是否与痴呆发生率降低相关。参加者来自独立和重要老年人的高级认知训练（ACTIVE）研究（n = 2,802）。突发性痴呆症的定义是结合访谈和基于表现的方法。生存分析被用来确定主动治疗是否在5年的随访期间影响了痴呆的发生率。共有189名参与者达到了痴呆事件的标准。预测发生痴呆的基线因素包括年龄，男性，非裔美国人种族，受教育年限短，未婚关系，未饮酒，MMSE差，SF-36身体机能差，抑郁症状，糖尿病和中风（全部p <.05）。具有显着预测事件痴呆症和训练组的多变量模型显示，认知训练与较低的事件痴呆率无关。随访5年后，认知训练并未影响痴呆的发生率。为了充分探索认知训练在预防痴呆发作中的预防能力，可能需要更长的随访或加强训练。

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