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Alternate calibration method of radiochromic EBT3 film for quality assurance verification of clinical radiotherapy treatments

机译:用于临床放疗治疗质量保证验证的放射变色EBT3膜的替代校准方法

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摘要

EBT3 film is utilized as a dosimetry quality assurance tool for the verification of clinical radiotherapy treatments. In this work, we suggest a percentage-depth-dose (PDD) calibration method that can calibrate several EBT3 film pieces together at different dose levels because photon beams provide different dose levels at different depths along the axis of the beam. We investigated the feasibility of the film PDD calibration method based on PDD data and compared the results those from the traditional film calibration method. Photon beams at 6 MV were delivered to EBT3 film pieces for both calibration methods. For the PDD-based calibration, the film pieces were placed on solid phantoms at the depth of maximum dose (dmax) and at depths of 3, 5, 8, 12, 17, and 22 cm, and a photon beam was delivered twice, at 100 cGy and 400 cGy, to extend the calibration dose range under the same conditions. Fourteen film pieces, to maintain their consistency, were irradiated at doses ranging from approximately 30 to 400 cGy for both film calibrations. The film pieces were located at the center position on the scan bed of an Epson 1680 flatbed scanner in the parallel direction. Intensity-modulated radiation therapy (IMRT) plans were created, and their dose distributions were delivered to the film. The dose distributions for the traditional method and those for the PDD-based calibration method were evaluated using a Gamma analysis. The PDD dose values using a CC13 ion chamber and those obtained by using a FC65-G Farmer chamber and measured at the depth of interest produced very similar results. With the objective test criterion of a 1% dosage agreement at 1 mm, the passing rates for the four cases of the three IMRT plans were essentially identical. The traditional and the PDD-based calibrations provided similar plan verification results. We also describe another alternative for calibrating EBT3 films, i.e., a PDD-based calibration method that provides an easy and time-saving approach to film calibration.
机译:EBT3膜被用作剂量学质量保证工具,用于验证临床放疗治疗。在这项工作中,我们建议使用百分比深度剂量(PDD)校准方法,该方法可以以不同的剂量水平一起校准多个EBT3胶片,因为光子束沿光束轴的不同深度提供不同的剂量水平。我们基于PDD数据研究了胶片PDD校准方法的可行性,并比较了传统胶片校准方法的结果。对于两种校准方法,将6 MV的光子束传送到EBT3胶片。对于基于PDD的校准,将胶片片段以最大剂量(dmax)的深度和3、5、8、12、17和22 cm的深度放在实心模型上,并发出两次光子束,在100 cGy和400 cGy时,可以在相同条件下扩展校准剂量范围。为了保持膜的一致性,以两次膜校准的约30至400 cGy的剂量照射了十四个膜片。胶片在平行方向上位于Epson 1680平板扫描仪的扫描床上的中心位置。创建了调强放射治疗(IMRT)计划,并将其剂量分布传递给胶片。使用Gamma分析评估了传统方法和基于PDD的校准方法的剂量分布。使用CC13离子室和通过使用FC65-G Farmer室获得并在目标深度处测量的PDD剂量值产生了非常相似的结果。以客观的测试标准为1 mm剂量协定为1%,三个IMRT计划的四个案例的通过率基本相同。传统的和基于PDD的校准提供了相似的计划验证结果。我们还描述了另一种用于校准EBT3胶片的替代方法,即基于PDD的校准方法,该方法提供了一种简便且省时的胶片校准方法。

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