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Differential X-ray phase-contrast imaging with a grating interferometer using a laboratory X-ray micro-focus tube

机译:使用实验室X射线微聚焦管的光栅干涉仪进行差分X射线相衬成像

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X-ray phase-contrast imaging can provide images with much greater soft-tissue contrast than conventional absorption-based images. In this paper, we describe differential X-ray phase-contrast images of insect specimens that were obtained using a grating-based Talbot interferometer and a laboratory X-ray source with a spot size of a few tens of micrometers. We developed the interferometer on the basis of the wavelength, periods, and height of the gratings; the field of view depends on the size of the grating, considering the refractive index of the specimen. The phase-contrast images were acquired using phase-stepping methods. The phase contrast imaging provided a significantly enhanced soft-tissue contrast compared with the attenuation data. The contour of the sample was clearly visible because the refraction from the edges of the object was strong in the differential phase-contrast image. Our results demonstrate that a grating-based Talbot interferometer with a conventional X-ray tube may be attractive as an X-ray imaging system for generating phase images. X-ray phase imaging obviously has sufficient potential and is expected to soon be a great tool for medical diagnostics.
机译:X射线相衬成像可以为图像提供比常规基于吸收的图像更大的软组织对比度。在本文中,我们描述了使用基于光栅的Talbot干涉仪和光斑大小为几十微米的实验室X射线源获得的昆虫标本的差分X射线相衬图像。我们根据光栅的波长,周期和高度开发了干涉仪。考虑到样品的折射率,视场取决于光栅的尺寸。使用相位步进方法获取相位对比图像。相较于衰减数据,相衬成像提供了显着增强的软组织衬度。样品的轮廓清晰可见,因为在微分相差图像中,物体边缘的折射很强。我们的结果表明,具有常规X射线管的基于光栅的Talbot干涉仪可能是吸引人的X射线成像系统,用于生成相位图像。 X射线相位成像显然具有足够的潜力,有望很快成为医学诊断的重要工具。

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