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首页> 外文期刊>Journal of the Korean Society of Food Science and Nutrition >Effects of Herbal Mixture Extracts Containing Angelica gigas Nakai and Cuscuta chinensis Lam. on Menopausal Symptoms in Ovariectomized Rats
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Effects of Herbal Mixture Extracts Containing Angelica gigas Nakai and Cuscuta chinensis Lam. on Menopausal Symptoms in Ovariectomized Rats

机译：当归中草药当归和中药龙舌兰的混合提取物的作用。去卵巢大鼠的更年期症状

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摘要

During menopause, elderly woman experience physical and emotional symptoms, including hot flashes, night sweats, weight gain, vaginal dryness, and mood swings. In this study, we investigated the effects of mixed herbal extracts containing Angelica gigas Nakai and Cuscuta chinensis Lam. on menopause symptoms in ovariectomized (OVX) rats. Daily oral treatments of 500 mg/kg and 1,000 mg/kg in OVX rats for 8 weeks significantly reduced weight gain, inhibited hepatic lipid accumulation, and lowered serumlipid levels comparable to the effects induced by estradiol treatments. Mixed herbal extracts (named Jaeummidan) also prevented vaginal dryness as measured by increased vaginal weight. Increased vaginal weight was associated with enlarged epithelium thickness. These data show the preventive actions of Jaeummidan against menopause symptoms and further suggest the possibility of developing functional ingredients in elderly human populations experiencing menopause symptoms.
机译：绝经期间，老年妇女会出现身体和情绪症状，包括潮热，盗汗，体重增加，阴道干燥和情绪波动。在这项研究中，我们调查了含有当归Nakai和中国Cu丝（Cuscuta chinensis Lam）的混合草药提取物的作用。卵巢切除（OVX）大鼠的更年期症状OVX大鼠每天口服500 mg / kg和1,000 mg / kg的药物治疗8周，与雌二醇治疗相比，可显着降低体重增加，抑制肝脂质蓄积并降低血脂水平。混合草药提取物（名为Jaeummidan）还可以防止阴道干燥，这是通过增加阴道重量来衡量的。阴道重量增加与上皮厚度增加有关。这些数据表明Jaeummidan对更年期症状的预防作用，并进一步表明在出现更年期症状的老年人中开发功能成分的可能性。

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