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首页> 外文期刊>Journal of the Korean Society of Food Science and Nutrition >Effect of Cynanchi wilfordii Radix Extracts on Lipid Compositions and Blood Pressure in Spontaneously Hypertensive Rats
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Effect of Cynanchi wilfordii Radix Extracts on Lipid Compositions and Blood Pressure in Spontaneously Hypertensive Rats

机译：白花蛇舌草提取物对自发性高血压大鼠脂质组成和血压的影响

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摘要

The purpose of this study was to observe the effects of Cynanchi wilfordii Radix extracts (CRE) on the improvement of the lipid compositions and blood pressure level in spontaneously hypertensive rats (SHR) fed an experimental diet for 5 weeks. The rats were divided into 3 groups: a control group, a 0.5% CRE treated group, and a 1% CRE treated group. Consumption of CRE extract for 5 weeks in SHR significantly suppressed blood pressure rise with aging (p<0.05). After eating the experimental diets, thetriglycerides in serum was significantly lower in the CRE group than that in the control group. The fasting glucose levels of the 0.5% and 1% CRE group had a tendency to be lower compared with those of the control group. Total cholesterol, HDL-cho-lesterol and HTR (HDL-cholesterol/total cholesterol) of the SHR in the 0.5% and 1% CRE diet were significantly increased compared to the control diet. Thus, long term consumption of CRE might be beneficial in lowering high blood pressure and the improvement of lipid metabolism in SHR rats.
机译：这项研究的目的是观察西洋参提取物（CRE）对以实验饮食喂养5周的自发性高血压大鼠（SHR）脂质组成和血压水平的改善作用。将大鼠分为三组：对照组，0.5％CRE治疗组和1％CRE治疗组。在SHR中食用CRE提取物5周可显着抑制衰老引起的血压升高（p <0.05）。进食实验饮食后，CRE组的血清甘油三酯明显低于对照组。与对照组相比，CRE组0.5％和1％的空腹血糖水平有降低的趋势。与对照饮食相比，0.5％和1％CRE饮食中SHR的总胆固醇，HDL-胆固醇和HTR（HDL-胆固醇/总胆固醇）显着增加。因此，长期服用CRE可能有助于降低SHR大鼠的高血压和改善脂质代谢。

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