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首页> 外文期刊>Journal of Veterinary Dentistry >Feline Oral Squamous Cell Carcinoma: Clinical Manifestations and Literature Review
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Feline Oral Squamous Cell Carcinoma: Clinical Manifestations and Literature Review

机译：猫口腔鳞状细胞癌：临床表现和文献复习。

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Squamous cell carcinoma (SCC) is the most commonly encountered malignant oral tumor in cats. The etiology of this locally invasive tumor is likely multifactorial. Several risk factors have been identified, including the use of flea collars, and a history of feeding canned food and canned tuna. Clinical signs vary depending on tumor location. The tumor commonly arises from the gingiva and mucosa of the maxilla, mandible, tongue, sublingual area, or tonsillar region. Maxillary SCC commonly presents clinically as an ulcerative lesion, whereas mandibular SCC is commonly proliferative, expansile, and firm. Lingual/sublingual SCC may be ulcerative, necrotic, infiltrative, or proliferative. In general, feline oral SCC is an invasive and malignant neoplasm regardless of its location. Surgery, radiation therapy, chemotherapy and combinations thereof have been attempted with rarely a satisfactory response. Currently, cures are obtained only in a small subset of cats whose tumors are amenable to complete resection, or where resection with microscopic residual disease is followed by definitive radiation therapy. A multimodal treatment approach likely offers the best chance of success. For cats with advanced disease, palliative care may improve patients' quality of life, albeit transiently. Sequelae associated with tumor progression and local tissue destruction often result in euthanasia of feline patients with oral SCC
机译：鳞状细胞癌（SCC）是猫中最常见的恶性口腔肿瘤。这种局部浸润性肿瘤的病因可能是多因素的。已经确定了几个风险因素，包括使用跳蚤项圈，喂食罐头食品和罐头金枪鱼的历史。临床体征因肿瘤部位而异。肿瘤通常起源于上颌，下颌，舌，舌下或扁桃体区域的牙龈和粘膜。上颌鳞癌在临床上通常表现为溃疡性病变，而下颌鳞癌通常是增生，扩张和坚硬的。舌/舌下SCC可能是溃疡性，坏死性，浸润性或增生性。通常，猫口腔SCC不论其位置如何，都是侵袭性和恶性肿瘤。已经尝试了很少有令人满意的反应的手术，放射疗法，化学疗法及其组合。目前，只有在一小部分猫的肿瘤可以完成切除的猫中才能治愈，或者在进行显微残留病的切除后再进行明确的放射治疗。多模式治疗方法可能会提供最大的成功机会。对于患有晚期疾病的猫，姑息治疗可能会暂时改善患者的生活质量。与肿瘤进展和局部组织破坏相关的后遗症通常导致猫患有口腔鳞状细胞癌的安乐死

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