A mechanism accounting for independence on starting length of tension increase in ramp stretches of active skeletal muscle at short half-sarcomere lengths.

Till O; Siebert T; Blickhan R

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A mechanism accounting for independence on starting length of tension increase in ramp stretches of active skeletal muscle at short half-sarcomere lengths.

机译：一种机制，可以解释半骨骼肌短长度时活动骨骼肌的斜道伸展中张力增加的起始长度的独立性。

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Based on previous experimental results of independence on starting length of the tension gradient in constant-velocity stretches of active skeletal muscle at muscle lengths including the ascending limb and the plateau of the tension-length relation, a possible physiological mechanism determining the tension increase in lengthening active muscle is discussed. Considering the sliding filament theory, it is suggested that the tension-length relation of a half-sarcomere in lengthening contractions is different from that in isometric contractions. The assumed mechanism predicts, among others, that the thick filament retains its shortened length in lengthening contractions starting from a half-sarcomere length where this filament is compressed. An example model is implemented and checked with simulations.

机译：根据以前的实验结果，在活动肌肉骨骼肌在恒速拉伸过程中，在包括上肢伸展和高原长度的肌肉长度等速拉伸过程中，张力梯度起始长度的独立性，可能的生理机制决定了拉长过程中拉力的增加讨论了活跃的肌肉。考虑滑动丝理论，建议在延长收缩中半肌节的张力-长度关系不同于等距收缩中的张力-长度关系。除其他因素外，假定的机理预测，从延长该细丝被压缩的半肌节长度开始，粗细丝在延长的收缩中保持其缩短的长度。实现了示例模型，并通过仿真进行了检查。

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《Journal of Theoretical Biology》 |2010年第1期|共7页
作者
Till O; Siebert T; Blickhan R;
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1. A mechanism accounting for independence on starting length of tension increase in ramp stretches of active skeletal muscle at short half-sarcomere lengths. [J] . Till O, Siebert T, Blickhan R Journal of Theoretical Biology . 2010,第1期

机译：一种机制，可以解释半骨骼肌短长度时活动骨骼肌的斜道伸展中张力增加的起始长度的独立性。
2. Muscle function of knee extensors and flexors after stroke is selectively impaired at shorter muscle lengths. [J] . Horstman A, Gerrits K, Beltman M, Journal of rehabilitation medicine : . 2009,第5期

机译：中风后膝部伸肌和屈肌的肌肉功能在较短的肌肉长度上有选择地受损。
3. Partial protection against muscle damage by eccentric actions at short muscle lengths. [J] . Nosaka K, Newton M, Sacco P, Medicine and science in sports and exercise . 2005,第5期

机译：在较短的肌肉长度上通过偏心动作对肌肉造成的部分保护。
4. The Length-tension Relations Of A Load Moving (ISOTONIC) Skeletal Muscle [C] . Solonionow M., Baratta R., Best R., Engineering in Medicine and Biology Society, 1991. Vol.13: 1991., Proceedings of the Annual International Conference of the IEEE . 1991

机译：负荷运动（等渗）骨骼肌的长度-张力关系
5. Mechanisms underlying the protection from contraction -induced skeletal muscle injury provided by exercising with passive stretches [D] . Lockhart, Nicole C. 2006

机译：被动伸展运动可预防收缩引起的骨骼肌损伤的机制
6. Sarcomere length-tension relations of frog skinned muscle fibres during calcium activation at short lengths. [O] . R L Moss 1979

机译：短距离钙激活过程中青蛙皮肤肌纤维的肌小节长度-张力关系。
7. A mechanism accounting for independence on starting length of tension increase in ramp stretches of active skeletal muscle at short half-sarcomere lengths [O] . Olaf Till, Tobias Siebert, Reinhard Blickhan 2010

机译：一种机制占独立于悬崖延伸长度的独立性，斜坡延伸长半肉卷长度

A mechanism accounting for independence on starting length of tension increase in ramp stretches of active skeletal muscle at short half-sarcomere lengths.

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