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首页> 外文期刊>Journal of toxicology-Clinical toxicology >Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: Observations in one case and implications for mechanism of toxicity
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Recurrent life-threatening ventricular dysrhythmias associated with acute hydrofluoric acid ingestion: Observations in one case and implications for mechanism of toxicity

机译：急性摄入氢氟酸伴发危及生命的反复性心律失常：1例观察结果及其对毒性机制的影响

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Introduction. Hydrofluoric acid (HF) is a weak inorganic acid used for etching and as rust remover. Systemic toxicity is manifested as ventricular dysrhythmias. The mechanisms for these dysrhythmias are not well elucidated. Case report. An 82-year-old woman ingested 8 ounces of 7% HF. Shortly after emergency department (ED) arrival, she became pulseless, developing recurrent ventricular dysrhythmias. She was defibrillated 17 times and received several doses of calcium, magnesium, and lidocaine. After three hours, she returned to sustained NSR. She was discharged home after four days. Discussion. The electrocardiographic findings in this patient demonstrate hypocalcemia, which has been implicated as the culprit in HF-induced arrhythmias. However, despite correction of the hypocalcemia, the ventricular arrhythmias persisted. The proposed mechanisms of systemic HF toxicity and the relevant literature are discussed. Conclusion. Ventricular dysrhythmias due to HF toxicity seem to be independent of either hypocalcemia or hyperkalemia. Systemic toxicity after ingestions may be delayed and precipitous.
机译：介绍。氢氟酸（HF）是一种弱无机酸，用于蚀刻和除锈剂。全身毒性表现为心律不齐。这些心律失常的机制尚不清楚。案例报告。一名82岁的女性摄入了8盎司的7％HF。急诊科（ED）到达后不久，她变得无脉搏，发展为反复发作的心律不齐。对她进行了17次除纤颤，并多次服用钙，镁和利多卡因。三个小时后，她恢复了持续的NSR。四天后她出院了。讨论。该患者的心电图检查结果显示血钙过低，这被认为是HF诱发心律不齐的罪魁祸首。然而，尽管低钙血症得到纠正，但室性心律失常仍然持续。讨论了系统性HF毒性的拟议机制和相关文献。结论。 HF毒性引起的心律失常似乎与低钙血症或高钾血症无关。食入后的全身毒性可能会延迟且严重。

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