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首页> 外文期刊>Journal of Veterinary Diagnostic Investigation >Comparing citrated native, kaolin-activated, and tissue factor-activated samples and determining intraindividual variability for feline thromboelastography.
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Comparing citrated native, kaolin-activated, and tissue factor-activated samples and determining intraindividual variability for feline thromboelastography.

机译：比较柠檬酸化的天然，高岭土激活和组织因子激活的样品，并确定猫血栓弹性成像的个体差异。

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摘要

Thromboelastography (TEG) is a point-of-care whole blood test of hemostasis. While TEG is becoming more widely used in veterinary medicine, few studies describe the use of TEG in cats. The objectives of the current study were to: (1) document the range of TEG variables produced in healthy cats using 3 sample types (citrated native, kaolin-activated, and tissue factor-activated), and (2) determine if there was a significant difference between 2 separate samples obtained from individual healthy cats on the same day. Jugular venipuncture was performed in 20 cats, and citrated blood collected for TEG. TEG analysis was performed on citrated native, kaolin-activated, and tissue factor-activated blood for each sample. Two hours later, the procedure was repeated from the opposite jugular vein, yielding a total of 120 analyses. Reaction time (R), alpha angle ( alpha ), kappa value ( kappa ), and maximum amplitude (MA) were recorded from each tracing. No significant differences were found between TEG tracings from the first and second venipuncture samples. Significant differences were found between sample types for R, alpha , kappa , and MA. Means for citrated native/kaolin-activated/tissue factor-activated methods were R=4.1/3.7/0.6 min; kappa =2.5/1.8/2.2 min; alpha =59.9/65.1/70.4 degrees; MA=47.4/49.9/44.7 mm. A limitation of this study was the small number of cats used. Thromboelastography analysis may be a suitable method of evaluating hemostasis in cats.
机译：血栓弹力描记术（TEG）是即时止血的即时医疗检查。尽管TEG越来越广泛地用于兽医，但是很少有研究描述TEG在猫中的使用。本研究的目的是：（1）使用3种样品类型（柠檬酸天然，高岭土激活和组织因子激活）记录健康猫体内产生的TEG变量的范围，以及（2）确定是否存在在同一天从两只健康猫身上得到的2个独立样本之间的显着差异。在20只猫中进行颈静脉穿刺，并收集柠檬酸血用于TEG。对每个样品的柠檬酸化天然血，高岭土激活血和组织因子激活血进行TEG分析。两个小时后，从相反的颈静脉重复该过程，总共进行了120次分析。从每次追踪记录反应时间（ R ），α角（α），κ值（κ）和最大振幅（MA）。在第一和第二次静脉穿刺样本的TEG描迹之间未发现显着差异。发现 R ，alpha，kappa和MA的样本类型之间存在显着差异。柠檬酸天然/高岭土活化/组织因子活化方法的平均值为 R = 4.1 / 3.7 / 0.6 min;卡伯= 2.5 / 1.8 / 2.2分钟; alpha = 59.9 / 65.1 / 70.4度; MA = 47.4 / 49.9 / 44.7毫米。这项研究的局限性是使用的猫只很少。血栓弹力图分析可能是评估猫的止血效果的合适方法。

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