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首页> 外文期刊>Journal of Veterinary Diagnostic Investigation >Disseminated Bovine viral diarrhea virus in a persistently infected alpaca (Vicugna pacos) cria
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Disseminated Bovine viral diarrhea virus in a persistently infected alpaca (Vicugna pacos) cria

机译:在持续感染的羊驼(Vicugna pacos)cria中传播牛病毒性腹泻病毒

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摘要

Bovine viral diarrhea virus (BVDV) is an emerging infectious pathogen of concern to the alpaca industry. A 4-month-old, intact, male alpaca cria was diagnosed as persistently infected with BVDV on the basis of repeated positive antemortem polymerasechain reaction (PCR) and virus isolation (VI) assays and negative serologic titers to BVDV. Immunohistochemistry, real-time reverse transcription PCR, and VI performed on tissues collected at necropsy demonstrated disseminated BVDV-1b infection. Virus was detected in multiple tissues, including parotid salivary gland, testes, prostate, kidneys, skin, and gastrointestinal tract. Demonstration of BVDV in previously unreported tissues suggests additional potential routes of BVDV transmission in alpacas.
机译:牛病毒性腹泻病毒(BVDV)是羊驼业关注的一种新兴传染病原体。根据反复的前死前聚合酶链反应(PCR)和病毒分离(VI)分析以及BVDV血清学滴度阴性,诊断出一个4个月大的完整雄性羊驼连续感染BVDV。尸检时收集的组织进行的免疫组织化学,实时逆转录PCR和VI证实为散布性BVDV-1b感染。在多种组织中检测到病毒,包括腮腺唾液腺,睾丸,前列腺,肾脏,皮肤和胃肠道。在以前未报告的组织中BVDV的证实表明羊驼中BVDV传播的其他潜在途径。

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