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首页> 外文期刊>Journal of voice: official journal of the Voice Foundation >Glucocorticoids for vocal fold disease: A survey of otolaryngologists
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Glucocorticoids for vocal fold disease: A survey of otolaryngologists

机译：糖皮质激素治疗声带疾病：耳鼻喉科医生的调查

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Objective/Hypothesis: Glucocorticoids (GCs) are commonly used in the treatment of laryngeal disorders despite the absence of clear guidelines regarding their use. We sought to assess clinical practice patterns regarding GC use for various vocal fold diseases and to ascertain factors underlying the selection of particular GCs for different vocal fold pathology. Study Design: Prospective, survey. Methods: A web-based 20-question survey querying clinical indications for GC use and other factors influencing decision making in GC administration was distributed to 5280 otolaryngologists via e-mail using a commercially available database. Results: The overall response rate for the survey was 4% (212/5280). Of the respondents, 99% reported GCs to be valuable in their practice. Previous experience/results, familiarity, and use in practice (68%, 54%, and 37%, respectively) were the most commonly cited reasons for choosing a particular GC; pharmacokinetic profile and academic literature were infrequently cited reasons. Fifty-four percent of respondents were more likely to prescribe GCs for vocal performers compared with other patients. Additionally, most respondents stated that the potential for side effects only occasionally prevented GC utilization. Conclusions: GC prescription practices vary greatly among otolaryngologists. Drug choice appears to be driven primarily by clinician preference and personal experience rather than by specific pharmacologic or physiologic rationale. These findings likely reflect the current lack of well-constructed studies in the laryngology literature to guide GC selection and administration for benign disorders of the larynx and highlight an important potential area for future studies.
机译：目的/假设：尽管缺乏明确的使用指南，糖皮质激素（GCs）通常用于治疗喉部疾病。我们试图评估有关各种声带疾病使用GC的临床实践模式，并确定针对不同声带病理学选择特定GC的基础因素。研究设计：前瞻性调查。方法：使用可商购的数据库，通过电子邮件将基于网络的20个问题的调查，询问有关GC使用的临床指征以及影响GC管理决策的其他因素，并通过电子邮件将其分发给5280名耳鼻喉科医生。结果：调查的总体答复率为4％（212/5280）。在受访者中，有99％的受访者表示GC在他们的实践中很有价值。先前的经验/结果，熟悉程度和实际使用率（分别为68％，54％和37％）是选择特定GC的最常见原因;药代动力学概况和学术文献很少被引用。与其他患者相比，有54％的受访者更有可能为表演者开出GC。此外，大多数受访者表示，潜在的副作用仅偶尔阻止了GC的利用。结论：耳鼻喉科医生的GC处方做法差异很大。药物选择似乎主要是由临床医生的偏好和个人经验所驱动，而不是由特定的药理或生理原理所驱动。这些发现可能反映了喉科学文献中目前缺乏结构完善的研究，以指导GC对喉良性疾病的选择和给药，并突出了未来研究的重要潜在领域。

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