...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical otolaryngology: official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery >Treatment and prognostic factors of papillary thyroid microcarcinoma.
【24h】

Treatment and prognostic factors of papillary thyroid microcarcinoma.

机译：甲状腺乳头状微癌的治疗和预后因素。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To discuss the prognostic factors and outcomes of treatment in patients diagnosed with papillary thyroid microcarcinoma. DESIGN: Retrospective observational case review. SETTING: Department of Otorhinolaryngology of the tertiary referral teaching hospital of Parma. PARTICIPANTS: Ninety-seven patients diagnosed with PTMC and surgically treated between January 1998 and December 2007. MAIN OUTCOME MEASURES: Clinical and histopathological characteristics of the study group were identified and statistically analysed. RESULTS: No cancer-related deaths were registered. Incidence of recurrent disease was 9% after a 43 month mean follow-up (range 12-120). Univariate analysis detected that metastases in neck lymph nodes at diagnosis (p = 0.025), a tumour >5 mm in size (p = 0.011), the presence of bilateral tumoural foci (p = 0.007), the presence of capsular invasion (p = 0.001), and the presence of vascular invasion (p = 0.004) were related to recurrent disease. On multivariate analysis, the presence of bilateral tumoural foci (p = 0.030), and the presence of capsular invasion (p = 0.005) were significantly related to tumour recurrence. CONCLUSION: The prognosis for patients with papillary thyroid microcarcinoma in this series was excellent, with a 100% survival rate and minimal surgical-related morbidity. Nevertheless, approximately 10% of patients developed recurrent disease; aggressive treatment may be justified depending on the presence or absence of prognostic risk factors.
机译：目的：探讨甲状腺乳头状微癌患者的预后因素和治疗结果。设计：回顾性观察病例回顾。单位：帕尔马第三级转诊教学医院耳鼻咽喉科。参加者：1998年1月至2007年12月，经诊断为PTMC并经手术治疗的97例患者。主要观察指标：对研究组的临床和组织病理学特征进行鉴定并进行统计学分析。结果：未发现与癌症相关的死亡。平均随访43个月（范围12-120），复发疾病的发生率为9％。单因素分析检测到诊断时发现颈部淋巴结转移（p = 0.025），肿瘤大小> 5 mm（p = 0.011），双侧肿瘤灶存在（p = 0.007），包膜浸润（p = 0.001）和血管浸润（p = 0.004）与复发疾病有关。在多变量分析中，双侧肿瘤灶的存在（p = 0.030）和包膜浸润的存在（p = 0.005）与肿瘤复发显着相关。结论：该系列甲状腺乳头状微癌患者的预后良好，生存率100％，与手术相关的发病率极低。然而，大约有10％的患者会复发。根据是否存在预后风险因素，积极治疗可能是合理的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号