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首页> 外文期刊>Journal of vascular and interventional radiology: JVIR >Contrast medium administration in the elderly patient: is advancing age an independent risk factor for contrast nephropathy after angiographic procedures?
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Contrast medium administration in the elderly patient: is advancing age an independent risk factor for contrast nephropathy after angiographic procedures?

机译:老年患者的造影剂管理:年龄增长是造影检查后造影剂肾病的独立危险因素吗?

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摘要

Contrast medium-induced nephropathy (CMIN) is the third leading cause of hospital-acquired acute renal dysfunction. Even if the number of patients over 75 years of age undergoing diagnostic and/or interventional procedures and requiring administration of contrast medium (CM) is growing constantly, at present there is no definitive consensus regarding the role of advancing age and related morphologic or functional renal changes as an independent risk factor for CMIN. The authors review the evidence from recent medical literature on the definition, pathophysiology, and clinical presentation of CMIN as well as therapeutic approaches to its prophylaxis. Attention is focused on advancing age as a preexisting physiologic condition that is, per se, able to predispose the patient to CM-induced renal impairment, assuming that every elderly patient is potentially at risk for CMIN.
机译:造影剂诱发的肾病(CMIN)是医院获得性急性肾功能不全的第三大原因。即使接受诊断和/或干预性手术且需要服用造影剂(CM)的75岁以上的患者人数在不断增加,但对于提高年龄以及相关的形态学或功能性肾功能尚无明确共识变化是CMIN的独立风险因素。作者回顾了最近医学文献中有关CMIN的定义,病理生理和临床表现以及预防CMIN的治疗方法的证据。假定将每名老年患者潜在地患CMIN的风险,注意力集中在提高年龄本身就是一种原有的生理状况上,这本身就能够使患者容易发生CM诱发的肾功能损害。

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