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首页> 外文期刊>Journal of trace elements in medicine and biology: Organ of the Society for Minerals and Trace Elements (GMS) >Organic and inorganic selenium supplementation to lactating mothers increase the blood and milk Se concentrations and Se intake by breast-fed infants.
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Organic and inorganic selenium supplementation to lactating mothers increase the blood and milk Se concentrations and Se intake by breast-fed infants.

机译：哺乳期母亲补充有机和无机硒会增加母乳喂养婴儿的血液和牛奶中硒的含量以及硒的摄入量。

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The aim of this study was to determine the effect of selenium (Se) supplementation to lactating women on Se concentrations and glutathione peroxidase (GSH-Px) activities in blood components of mothers and breast-fed infants and on milk Se levels and Se intake by breast-fed infants. Lactating mothers were supplied for 3 months with 200 micrograms Se/day in the form of yeast-Se (Y-Se) and sodium selenite. Initial blood and plasma Se levels of all women (n = 67) were 76.6 and 53.2 micrograms/L, respectively. After 3 months Se concentrations both in whole blood and in plasma from mothers and infants were significantly higher than the initial values. Y-Se exerts a stronger effects than selenite on blood and plasma Se levels. Initial milk Se concentration was 8.9 micrograms/L and after 1 month in both groups in reached a plateau at 14-16 micrograms/L. This resulted in an increase of Se intake in breast-fed infants from 6.1 to a plateau of 11-13 micrograms Se/day. GSH-Px activities in plasma and red cells of Y-Se group increased significantly and reached a plateau after 1 and 2 months, respectively, while in the selenite group the enzyme activities increased steadily throughout the entire period of the study. Selenite exerts a stronger effect on GSH-Px both in maternal and in infant blood components as compared with Y-Se. In milk the GSH-Px activity in the Y-Se group did not change during the study, while in the selenite group after 3 months it increased almost 2-fold compared to the initial value. In conclusion, this study shows that organic Se causes higher Se deposition than did the inorganic form.
机译：这项研究的目的是确定哺乳期妇女补充硒对母体和母乳喂养婴儿血液中的硒浓度和谷胱甘肽过氧化物酶（GSH-Px）活性以及牛奶中硒水平和硒摄入的影响。母乳喂养的婴儿。为哺乳期母亲提供3个月的200微克硒/天的硒-酵母（Y-Se）和亚硒酸钠形式。所有妇女（n = 67）的初始血液和血浆硒水平分别为76.6和53.2微克/升。 3个月后，母亲和婴儿的全血和血浆中的硒浓度均明显高于初始值。 Y-Se在血液和血浆Se水平上的作用比亚硒酸盐强。初始牛奶硒浓度为8.9微克/升，两组在1个月后达到14-16微克/升的稳定水平。这导致母乳喂养婴儿的硒摄入量从6.1增加到每天11-13微克硒的稳定水平。 Y-Se组血浆和红细胞中的GSH-Px活性显着增加，分别在1和2个月后达到平稳，而在亚硒酸盐组中，酶活性在整个研究过程中稳定增加。与Y-Se相比，亚硒酸盐对母体和婴儿血液成分中的GSH-Px都有更强的作用。在研究过程中，Y-Se组的牛奶中GSH-Px活性没有变化，而亚硒酸盐组3个月后，其GSH-Px活性则比初始值增加了近2倍。总之，这项研究表明，有机硒比无机形式引起的硒沉积更高。

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