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首页> 外文期刊>Journal of transcultural nursing: official journal of the Transcultural Nursing Society >Cross-Cultural Adaptation and Psychometric Assessment of the Liver Disease Symptom Index 2.0 to Measure Health-Related Quality of Life Among Iranian Patients With Chronic Hepatitis B
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Cross-Cultural Adaptation and Psychometric Assessment of the Liver Disease Symptom Index 2.0 to Measure Health-Related Quality of Life Among Iranian Patients With Chronic Hepatitis B

机译：跨文化适应和肝病症状指数2.0的心理计量学评估，以测量伊朗慢性乙型肝炎患者的健康相关生活质量

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摘要

Purpose: There are only a few measures to assess quality of life among patients with liver disorders. The aim of this study was to determine the psychometric properties of the Liver Disease Symptom Index Version 2.0 (LDSI 2.0), a disease specific measure of health-related quality of life (HRQOL), in Persian-speaking patients with chronic hepatitis B. Method: Using a cross-sectional design, 312 patients were recruited. Data were collected from the patients using the LDSI 2.0, Chronic Liver Disease Questionnaire, and EuroQol. Convergent and discriminant validity were investigated. Known-groups validity and factor structure of the scale were also determined. Receiver operating characteristics was used to discriminate patients based on their general health status. Results: Significant correlations were found between HRQOL measures. Disease duration, disease stage, and serum aspartate aminotransferase differentiated patients. Factor analysis determined a seven-factor solution that explained 70% of the total variance. Area under the curve in receiver operating characteristics analysis was 0.706; 95% confidence interval = [0.648, 0.764]. Conclusions: The LDSI2.0 is an appropriate HRQOL scale for use among Iranian patients with chronic hepatitis B based on its solid psychometric properties in this population.
机译：目的：只有少数方法可以评估肝病患者的生活质量。这项研究的目的是确定波斯语慢性乙型肝炎患者肝病症状指数2.0版（LDSI 2.0）的心理测量特性，这是一种针对疾病的健康相关生活质量（HRQOL）疾病特异性测量方法。 ：采用横断面设计，招募了312名患者。使用LDSI 2.0，慢性肝病问卷和EuroQol从患者收集数据。研究收敛效度和判别效度。还确定了已知人群的效度和量表的因素结构。接收者的操作特征用于根据患者的总体健康状况对其进行区分。结果：HRQOL度量之间发现显着相关性。疾病持续时间，疾病阶段和血清天冬氨酸转氨酶使患者分化。因子分析确定了可以解释总方差的70％的七因子解决方案。接收机工作特性分析中曲线下面积为0.706; 95％置信区间= [0.648，0.764]。结论：LDSI2.0是适合伊朗慢性乙型肝炎患者的HRQOL量表，因为它在该人群中具有坚实的心理特征。

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