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首页> 外文期刊>Journal of Zoo and Wildlife Medicine >NONFATAL CLINICAL PRESENTATION OF ELEPHANT ENDOTHELIOTROPIC HERPES VIRUS DISCOVERED IN A GROUP OF CAPTIVE ASIAN ELEPHANTS (ELEPHAS MAXIMUS)
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NONFATAL CLINICAL PRESENTATION OF ELEPHANT ENDOTHELIOTROPIC HERPES VIRUS DISCOVERED IN A GROUP OF CAPTIVE ASIAN ELEPHANTS (ELEPHAS MAXIMUS)

机译：一组亚洲捕获大象（大象最大）发现的大象内胚层疱疹病毒的非致命性临床表现

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Several different strains of elephant endotheliotropic herpes virus-1 (EEHV-1) have been identified via polymerase chain reaction (PCR) techniques in both African and Asian elephants. EEHV-1 has been identified in both cutaneous lesions in healthy African elephants and fatal cases of hemorrhagic syndrome in Asian elephants.(6) However, until now, no EEHV-1 strain has been identified or associated with otherwise healthy Asian elephants. This article describes recurrent nonendothelial lesions associated with EEHV-1 infection in a herd of Asian elephants not exhibiting fatal hemorrhagic syndrome. Genotypes of EEHV-1 strains, based on viral DNA polymerase and glycoprotein B, associated with fatal hemorrhagic syndrome, were compared to those identified in nonendothelial lesions. The same EEHV-1 genotypes were identified in fatal cases and mucosal lesions in otherwise healthy Asian elephants in this herd. Further studies of the Asian elephant immune system and virologic studies to determine the triggers of tissue tropism are needed before any conclusion can be reached.
机译：通过聚合酶链反应（PCR）技术已在非洲和亚洲大象中鉴定出几种不同的大象内皮型疱疹病毒1（EEHV-1）株。在健康的非洲象的皮肤病变和亚洲象的致命性出血综合征病例中均已发现EEHV-1。（6）然而，到目前为止，尚未发现EEHV-1株或与其他健康的亚洲象有关。本文介绍了一群未表现出致命出血综合征的亚洲象中与EEHV-1感染相关的复发性非内皮病变。将与致命性出血综合征相关的基于病毒DNA聚合酶和糖蛋白B的EEHV-1菌株的基因型与非内皮病变中鉴定的基因型进行了比较。在该病例群中其他健康亚洲象的致命病例和粘膜病变中鉴定出相同的EEHV-1基因型。在得出任何结论之前，需要对亚洲象的免疫系统进行进一步研究，并进行病毒学研究以确定组织趋向性的诱因。

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