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首页> 外文期刊>Journal of Zoo and Wildlife Medicine >Anesthesia of polar bears (Ursus maritimus) with zolazepam-tiletamine, medetomidine-ketamine, and medetomidine-zolazepam-tiletamine
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Anesthesia of polar bears (Ursus maritimus) with zolazepam-tiletamine, medetomidine-ketamine, and medetomidine-zolazepam-tiletamine

机译：北极熊（Ursus maritimus）用左拉西坦-左旋苯丙胺，美托咪定-氯胺酮和美托咪定-左拉西帕坦-左旋苯胺麻醉

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The anaesthetic effects of zolazepam-tiletamine (ZT) were compared with those of medetomidine-ketamine (MK) and medetomidine-zolazepam-tiletamine (MZT) in 93 free-ranging polar bears. The MZT combination was administered in smaller dose and volume,resulted in more rapid, safer, and more predictable induction, provided more reliable anaesthesia, and was safely reversed with atipamezole. Frequent occurrence of sudden recoveries during anaesthesia with MK limited the use of this combination. MK and MZT sometimes caused apnoea and bradycardia initially and hyperthermia at increased ambient temperatures. Hypoxaemia occurred transiently with all combinations. When anaesthesia with ZT and MK exceeded 1 h, frequent necessary top-up doses caused irregularphysiological function. It is concluded that ZT is best for short duration anaesthesia (<=1 h), but MZT is better for anaesthesia of longer duration and under circumstances where reversibility is desirable.
机译：在93只自由放养的北极熊中，比较了佐拉西p-维他命胺（ZT）与美托咪定-氯胺酮（MK）和美托咪定-佐拉西p-胆碱胺（MZT）的麻醉效果。 MZT组合以较小的剂量和体积施用，可导致更快，更安全和更可预测的诱导，提供更可靠的麻醉，并可以安全地与阿替哌唑逆转。 MK麻醉期间经常出现突然的恢复，限制了这种组合的使用。 MK和MZT有时最初会导致呼吸暂停和心动过缓，并在环境温度升高时引起体温过高。低氧血症在所有组合中均短暂发生。当ZT和MK麻醉超过1小时时，频繁的必要补充剂量会导致生理功能异常。结论是，ZT最好用于短期麻醉（<= 1 h），而MZT最好用于较长时间的麻醉并且需要可逆性。

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