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首页> 外文期刊>Clinical Orthopaedics and Related Research >Surgical treatment of grade I central chondrosarcoma.
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Surgical treatment of grade I central chondrosarcoma.

机译：Ⅰ级中心性软骨肉瘤的外科治疗。

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The grade of chondrosarcoma relates to the likelihood of local recurrence and metastases. Many Grade I chondrosarcomas behave benignly if aggressively, and the question arises regarding whether wide resection is essential to control the disease. We therefore asked whether intralesional surgery also could be extended to Grade I chondrosarcomas without an increase in recurrence. We retrospectively reviewed 31 patients with Grade I chondrosarcomas of the limbs. The minimum followup was 66 months (mean, 157 months; range, 66-296 months). None of the 16 patients treated by resection had recurrences during the followup and two of the 15 patients with intralesional excision had recurrences, both of which resolved with resection of the site involved by the recurrence without progression of the disease. The Musculoskeletal Tumor Society scores averaged 72% in patients treated with wide resection compared with 89% in the 15 patients treated by intralesional surgery. The two recurrences occurred in patients whose radiographs showed thinning of the cortex combined with bone enlargement and marked endosteal scalloping; histologic examination in these two patients also showed a correlation between radiographic aggressiveness and the presence of myxoid areas and hypercellularity. Level of Evidence: Level II, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.
机译：软骨肉瘤的级别与局部复发和转移的可能性有关。许多I级软骨肉瘤如果具有侵略性，则表现为良性，因此出现一个问题，即广泛切除对于控制该疾病是否必不可少。因此，我们询问是否可以在不增加复发率的情况下将病灶内手术扩大至I级软骨肉瘤。我们回顾性地回顾了31例四级软骨肉瘤患者。最小随访时间为66个月（平均157个月;范围66-296个月）。在随访期间，接受切除术的16例患者均未复发，而15例病灶内切除的患者中有2例复发，均通过切除所累及的部位而治愈，且无疾病进展。广泛切除的患者的骨骼肌肉肿瘤学会平均得分为72％，而病灶内手术的15例患者的平均得分为89％。两次复发发生在X线片显示皮质变薄并伴有骨增大和明显的骨内膜扇贝形的患者。在这两名患者中的组织学检查还显示出放射线摄动性与粘液样区域的存在和细胞过多之间的相关性。证据级别：II级，预后研究。有关证据水平的完整说明，请参见《作者指南》。

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