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首页> 外文期刊>Journal of women’s health >Generation C: prevalence of and risk factors for chlamydia trachomatis among adolescents and young women in Lima, Peru.
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Generation C: prevalence of and risk factors for chlamydia trachomatis among adolescents and young women in Lima, Peru.

机译：C代：秘鲁利马的青少年和年轻女性中沙眼衣原体的患病率和危险因素。

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OBJECTIVE: Adolescent and young adult women in urban, socioeconomically disadvantaged areas are at high risk of contracting sexually transmitted infections (STIs). We assessed associations of Chlamydia trachomatis (CT) infection with both traditional STI risk factors, and partner and partnership-related factors among low-income women in Lima, Peru, by age group. METHODS: In a cross-sectional analysis of CT infection among 1290 postpartum women, cervical swabs were collected for CT polymerase chain reaction (PCR) within 48 h after delivery, and a structured interview was completed. Multivariate logistic regression was used to evaluate risk factors for CT, with separate models stratified by age: adolescents (12-19 years), young women (20-24 years), and older women (>or=25 years). RESULTS: CT was detected in 9.6% of adolescents, 9.0% of young women, and 5.4% of older women (p = 0.03). Among adolescents, history of drug use (odds ratio [OR] = 5.62, 95% confidence interval [CI] 1.03-30.6) and short duration of current partnership (OR = 2.6, 95% CI 1.14-5.93) were the strongest predictors of CT infection. Among young women, younger age at coitarche (OR = 0.74 for each year older, 95% CI 0.60-0.91) and low income (OR = 2.40, 95% CI 1.04-5.55) were associated with CT, while self-report of ever using condoms was protective (OR = 0.22, 95% CI 0.08-0.61). Among older women, only younger age at coitarche was related to CT (OR = 0.85, 95% CI 0.75-0.97). CONCLUSIONS: Risk factors for CT among women in Lima, Peru, differed for adolescents, young women, and older women, which may reflect differences in biology and/or immunology of CT as well as variability in the occurrence of specific risk behaviors by age group.
机译：目的：城市，社会经济处于不利地位的地区的青少年和成年妇女极有可能感染性传播感染。我们按年龄组评估了秘鲁利马低收入女性中沙眼衣原体（CT）感染与传统性传播感染风险因素以及伴侣和伙伴关系相关因素的关联。方法：在1290名产后妇女的CT感染横断面分析中，在分娩后48小时内收集宫颈拭子进行CT聚合酶链反应（PCR），并完成了结构化访谈。多因素logistic回归用于评估CT的危险因素，并采用按年龄分层的单独模型：青少年（12-19岁），年轻妇女（20-24岁）和老年妇女（>或= 25岁）。结果：在9.6％的青少年，9.0％的年轻妇女和5.4％的老年妇女中检测到CT（p = 0.03）。在青少年中，吸毒史（优势比[OR] = 5.62，95％置信区间[CI] 1.03-30.6）和当前伴侣关系持续时间短（OR = 2.6，95％CI 1.14-5.93）是最有力的预测因素CT感染。在年轻女性中，CT年龄较低（OR = 0.74，每年每岁，OR = 0.74，95％CI 0.60-0.91）和低收入（OR = 2.40，95％CI 1.04-5.55），而自我报告永远使用避孕套具有保护作用（OR = 0.22，95％CI 0.08-0.61）。在年龄较大的女性中，只有年轻女性的耳鼻喉部与CT相关（OR = 0.85，95％CI 0.75-0.97）。结论：秘鲁利马妇女中CT的危险因素在青少年，年轻妇女和老年妇女中有所不同，这可能反映出CT的生物学和/或免疫学方面的差异以及特定年龄段特定危险行为发生的差异。

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