...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of women’s health >An open label pilot study of transcranial magnetic stimulation for pregnant women with major depressive disorder.
【24h】

An open label pilot study of transcranial magnetic stimulation for pregnant women with major depressive disorder.

机译：对患有严重抑郁症的孕妇进行经颅磁刺激的开放标签先导研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: Despite the data that major depressive disorder (MDD) is common during pregnancy and that pregnant women prefer nonmedication treatment options, there is a paucity of research examining alternative treatments for this special population. We present the results of an open label pilot study examining treatment with transcranial magnetic stimulation (TMS) in pregnant women with MDD. METHODS: Ten women with MDD in the second or third trimester of pregnancy were treated with 20 sessions of 1-Hz TMS at 100% of motor threshold (MT) to the right dorsolateral prefrontal cortex. The total study dose was 6000 pulses. Antenatal monitoring was performed during treatment sessions 1, 10, and 20. RESULTS: Seven of ten (70%) subjects responded (decrease >/=50% in Hamilton Depression Rating Scale [HDRS-17] scores). No adverse pregnancy or fetal outcomes were observed. All infants were admitted to the well baby nursery and were discharged with the mother. Mild headache was the only common adverse event and was reported by 4 of 10 (40%) subjects. CONCLUSIONS: TMS appears to be a promising treatment option for pregnant women who do not wish to take antidepressant medications.
机译：目的：尽管有数据表明妊娠期间严重抑郁症（MDD）很常见，而且孕妇更喜欢非药物治疗选择，但仍缺乏针对这种特殊人群研究替代治疗的研究。我们介绍了一项开放标签的先导研究的结果，该研究检查了经颅磁刺激（TMS）对MDD孕妇的治疗。方法：对10名在妊娠中期或中期妊娠MDD的妇女进行20次1-Hz TMS治疗，以100％的运动阈值（MT）到达右后外侧前额叶皮层。研究总剂量为6000脉冲。在治疗过程1、10和20期间进行了产前监测。结果：十名受试者中有七名（70％）有反应（汉密尔顿抑郁量表[HDRS-17]得分降低> / = 50％）。没有观察到不良妊娠或胎儿结局。所有婴儿均被收养到婴儿室，并随母亲出院。轻度头痛是唯一常见的不良事件，10名受试者中有4名（40％）报告。结论：对于不愿服用抗抑郁药的孕妇来说，TMS似乎是一种有前途的治疗选择。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号