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首页> 外文期刊>Journal of women’s health >Self-management, amitriptyline, and amitripyline plus triamcinolone in the management of vulvodynia.
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Self-management, amitriptyline, and amitripyline plus triamcinolone in the management of vulvodynia.

机译：自我管理，阿米替林和阿米替林加曲安奈德治疗外阴痛。

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OBJECTIVE: To conduct a prospective study to determine the efficacy of self-management interventions, amitriptyline, and amitriptyline plus topical triamcinolone in reducing vulvar pain in women with vulvodynia. METHODS: This was a randomized, prospective study of 53 women between the ages of 18 and 72 with vulvodynia. Participants undertook one of three treatment interventions for a period of 12 weeks: self-management, oral amitriptyline (10-20 mg/day), or topical triamcinolone plus oral amitriptyline (10-20 mg/day). The McGill Pain Questionnaire (MPQ) was used to measure changes in qualitative pain using the pain rating index (PRI) and in quantitative pain using the present pain intensity (PPI) scale. RESULTS: Of the 53 randomized subjects, 43 completed the trial. There were no statistically significant differences in PRI or PPI scores among the three treatment groups. Significant within-group differences were observed in the self-management group on the PRI and in the amitriptyline group on the PPI. CONCLUSIONS: This first randomized, prospective trial suggests that self-management has a modest effect and that low-dose amitriptyline (with and without topical triamcinolone) is not effective in reducing pain in women with vulvodynia.
机译：目的：进行一项前瞻性研究，以确定自我管理干预，阿米替林和阿米替林加局部曲安奈德在减轻外阴痛女性外阴痛中的功效。方法：这是一项随机，前瞻性研究，对53名18至72岁的女性外阴痛患者进行了前瞻性研究。参与者接受了三种治疗干预措施之一，为期12周：自我管理，口服阿米替林（10-20 mg /天）或局部曲安西龙加口服阿米替林（10-20 mg /天）。麦吉尔疼痛问卷（MPQ）用于使用疼痛等级指数（PRI）来测量定性疼痛的变化，并使用当前疼痛强度（PPI）量表来测量定量疼痛的变化。结果：在53名随机受试者中，有43名完成了试验。三个治疗组之间的PRI或PPI得分无统计学差异。在PRI的自我管理组和PPI的阿米替林组中观察到显着的组内差异。结论：这是第一项随机，前瞻性试验，表明自我管理作用适中，低剂量阿米替林（有或无外用曲安西龙）在减轻外阴痛患者的疼痛方面无效。

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