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首页> 外文期刊>Journal of women’s health >Sex differences in perceived life satisfaction and functional status one year after severe traumatic brain injury.
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Sex differences in perceived life satisfaction and functional status one year after severe traumatic brain injury.

机译：严重外伤性脑损伤一年后的感知生活满意度和功能状态的性别差异。

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AIMS: The primary aim of this study was to describe and compare perceived life satisfaction and perceived functional motor and cognitive status 1 year after severe traumatic brain injury (TBI) in males and females, adjusting for demographics and severity of injury. METHODS: Data of 297 participants were abstracted from the National Institute on Disability Rehabilitation and Research (NIDRR)-funded Traumatic Brain Injury Model Systems (TBIMS). Participants were aged 16-50, enrolled in the TBIMS study between the years 1998 and 2008, diagnosed with severe TBI (defined as having an initial Glasgow Coma Scale [GCS] score between 3 and 8), and with perceived life satisfaction and functional status data available at 1 year postinjury. Multiple linear regression models were used to estimate the association between sex, demographic variables, severity of injury, and the outcome variables. RESULTS: Our findings indicate that sex did not significantly influence perceived satisfaction with life or motor function 1 year after severe TBI. However, females had significantly better (p = 0.031) cognitive outcomes compared to males 1 year after severe TBI, after controlling for demographics and severity of injury. CONCLUSIONS: Findings suggest that females may have better perceived cognitive functional outcomes than males 1 year after severe TBI. Further longitudinal research, including measurement of hormonal levels, is needed to determine if hormones influence outcomes of severe TBI as well as the trajectory of these outcomes. A better understanding of sex differences in outcomes after TBI will help clinicians improve strategies for rehabilitation.
机译：目的：本研究的主要目的是描述和比较男性和女性严重外伤性脑损伤（TBI）一年后的感知生活满意度以及感知的功能性运动和认知状态，并根据人口统计学和损伤的严重程度进行调整。方法：297名参与者的数据摘自美国国家残疾人康复与研究学院（NIDRR）资助的创伤性脑损伤模型系统（TBIMS）。参与者年龄在16-50岁之间，参加了1998年至2008年之间的TBIMS研究，被诊断出患有严重的TBI（定义为初始格拉斯哥昏迷量表[GCS]评分在3到8之间），并具有感知的生活满意度和功能状态受伤后1年可获得的数据。使用多个线性回归模型来估计性别，人口统计学变量，伤害严重程度和结果变量之间的关联。结果：我们的研究结果表明，严重的TBI发生1年后，性别并未显着影响对生活或运动功能的满意感。但是，在控制了人口统计资料和受伤严重程度后，严重的TBI发生1年后，女性的认知结果明显好于男性（p = 0.031）。结论：研究结果表明，严重的TBI发生1年后，女性的认知功能结局可能比男性更好。需要进一步的纵向研究，包括激素水平的测定，以确定激素是否会影响严重TBI的预后以及这些预后的轨迹。更好地了解TBI后结局上的性别差异将有助于临床医生改善康复策略。

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