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首页> 外文期刊>Journal of women’s health >Practices that reduce the latina survival disparity after breast cancer
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Practices that reduce the latina survival disparity after breast cancer

机译:减少乳腺癌后拉丁裔生存差异的做法

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Objectives: Latina breast cancer patients are 20 percent more likely to die within 5 years after diagnosis compared with white women, even though they have a lower incidence of breast cancer, lower general mortality rates, and some better health behaviors. Existing data only examine disparities in the utilization of breast cancer care; this research expands the study question to which utilization factors drive the shorter survival in Latina women compared with white women. Methods: This longitudinal linked Surveillance Epidemiology and End Results (SEER)-Medicare cohort study examined early stage breast cancer patients diagnosed between 1992 and 2000 and followed for 5-11 years after diagnosis (N=44,999). Modifiable utilization factors included consistent visits to primary care providers and to specialists after diagnosis, consistent post-diagnosis mammograms, and receipt of initial care consistent with current standards of care. Results: Of the four utilization factors potentially driving this disparity, a lack of consistent post-diagnosis mammograms was the strongest driver of the Latina breast cancer survival disparity. Consistent mammograms attenuated the hazard of death from 23% [hazard ratio, HR, (95% confidence interval, 95%CI)=1.23 (1.1,1.4)] to a nonsignificant 12% [HR (95%CI)=1.12 (0.7,1.3)] and reduced the excess hazard of death in Latina women by 55%. Effect modification identified that visits to primary care providers have a greater protective impact on the survival of Latina compared to white women [HR (95%CI)=0.9 (0.9,0.9)]. Conclusions: We provide evidence that undetected new or recurrent breast cancers due to less consistent post-diagnosis mammograms contribute substantially to the long-observed Latina survival disadvantage. Interventions involving primary care providers may be especially beneficial to this population.
机译:目标:尽管白人乳腺癌患者的乳腺癌发病率较低,总体死亡率较低且健康行为较好,但与白人女性相比,确诊后5年内,拉丁裔乳腺癌患者死亡的可能性高出20%。现有数据仅检查了乳腺癌护理利用方面的差异;这项研究扩大了研究问题,即与白人女性相比,哪些利用因素导致拉丁裔女性的生存期较短。方法:这项纵向关联的监测流行病学和最终结果(SEER)-Medicare队列研究检查了1992年至2000年之间诊断出的早期乳腺癌患者,并在诊断后随访了5-11年(N = 44,999)。可利用的因素包括诊断后对基层医疗服务提供者和专家的持续拜访,诊断后的乳房X线照片的持续拜访以及与当前护理标准一致的初始护理的接受。结果:在可能导致这种差异的四个利用因素中,缺乏一致的诊断后乳房X线照片是拉美裔乳腺癌生存差异的最主要原因。一致的乳房X线照片将死亡危险从23%[危险比,HR,(95%置信区间,95%CI)= 1.23(1.1,1.4)]降低至不显着的12%[HR(95%CI)= 1.12(0.7) ,1.3)],将拉丁裔女性的死亡额外危险降低了55%。效果的改变表明,与白人女性相比,就诊基层医疗服务提供者对拉丁裔的生存具有更大的保护作用[HR(95%CI)= 0.9(0.9,0.9)]。结论:我们提供的证据表明,由于诊断后乳房X线照片的一致性较差,未检出的新发或复发性乳腺癌在很大程度上导致了长期以来观察到的拉丁裔生存劣势。涉及初级保健提供者的干预措施可能对该人群特别有益。

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