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首页> 外文期刊>Journal of women’s health >Is Carotid Stenosis in Women a Gender-Related Condition?
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Is Carotid Stenosis in Women a Gender-Related Condition?

机译：女性的颈动脉狭窄是否与性别有关？

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Background: We set out to study, through ultrasound examinations, the carotid bifurcation in men and women with/without carotid stenosis to look for anatomical and electrophysiologic differences. We evaluated other variables to look for differences that might explain the dissimilar behavior of this disease in the two sexes and the presence and impact of risk factors. Methods: We examined 974 subjects aged 25 to 88 years (478 men and 496 women) in whom we considered heart rate, smoking status, and the presence of hypertension, diabetes, hypercholesterolemia, and hypertriglyceridemia. Ultrasound examination of the neck vessels included measurement of intimal medial thickness (IMT), vessel diameter, and outflow area/inflow area ratio. We established plaque location, echogenicity and echostructure, and the percentage of stenosis owing to plaque and measured systolic velocity, flow direction, and the depth of detection of these parameters. We used the apnea and hyperpnea test to assess cerebrovascular reactivity. Results: Hypertension and hypercholesterolemia were the most frequent risk factors. Women had a higher heart rate, whereas men had significantly greater IMT. The presence of atheromatous plaque was significantly correlated with age in both sexes, with men having a higher prevalence of carotid plaques. The sexes differed significantly with regard to plaque location, echogenicity, echostructure, and intracranial circulation. Women had a slightly higher blood flow velocity in the intracranial arteries. Risk factors affected plaque formation and extent more in men than in women. Conclusions: These findings suggest that carotid stenosis is a gender-related trait.
机译：背景：我们开始通过超声检查研究患有/不患有颈动脉狭窄的男女的颈动脉分叉，以寻找解剖学和电生理学差异。我们评估了其他变量以寻找差异，这些差异可能解释了该病在两性中的不同行为以及危险因素的存在和影响。方法：我们检查了974名年龄在25至88岁之间的受试者（478名男性和496名女性），他们考虑了心率，吸烟状况以及高血压，糖尿病，高胆固醇血症和高甘油三酯血症的存在。颈部血管的超声检查包括内膜中层厚度（IMT），血管直径和流出面积/流入面积比的测量。我们建立了斑块的位置，回声性和回声结构，以及由于斑块引起的狭窄百分比，并测量了收缩速度，流向和这些参数的检测深度。我们使用了呼吸暂停和呼吸暂停测试来评估脑血管反应性。结果：高血压和高胆固醇血症是最常见的危险因素。女人的心率更高，而男人的IMT则更高。男女中年龄段与动脉粥样斑块的存在显着相关，而男性的颈动脉斑块患病率更高。在菌斑位置，回声，回声结构和颅内循环方面，性别存在显着差异。妇女的颅内动脉血流速度略高。危险因素影响斑块形成和程度的男性多于女性。结论：这些发现表明颈动脉狭窄是与性别有关的特征。

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