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首页> 外文期刊>Journal of the Physical Society of Japan >Enhanced Diffusion of Molecular Motors in the Presence of Adenosine Triphosphate and External Force
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Enhanced Diffusion of Molecular Motors in the Presence of Adenosine Triphosphate and External Force

机译:三磷酸腺苷和外力作用下分子马达的扩散增强

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摘要

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed periodically on a line, and the potential is switched stochastically from one parabola to another by a chemical reaction, which corresponds to the hydrolysis or synthesis of adenosine triphosphate (ATP) in motor proteins. It is found that the diffusion coefficient as a function of the force exhibits peaks. The mechanism of this diffusion enhancement and the possibility of observing it in F-1-ATPase, a biological rotary motor, are discussed.
机译:在简单的理论模型的基础上考虑了在恒定外力存在下分子电动机的扩散。电机由布朗粒子组成,该布朗粒子以周期性排列在一条线上的一系列抛物线电势移动,并且该电势通过化学反应从一个抛物线随机切换到另一个抛物线,这对应于三磷酸腺苷(ATP)的水解或合成在运动蛋白中。已经发现,作为力的函数的扩散系数显示出峰值。讨论了这种扩散增强的机理以及在生物旋转马达F-1-ATPase中观察到这种扩散的可能性。

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