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首页> 外文期刊>Clinical and experimental hypertension: CEH >Effects of orthostatic self-training on head-up tilt testing for the prevention of tilt-induced neurocardiogenic syncope: comparison of pharmacological therapy.
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Effects of orthostatic self-training on head-up tilt testing for the prevention of tilt-induced neurocardiogenic syncope: comparison of pharmacological therapy.

机译：体位自训练对抬头倾斜测试的影响，以防止倾斜诱发的神经心源性晕厥：药物治疗的比较。

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Although a wide variety of medical treatments for neurocardiogenic syncope have been proposed, therapy has largely been emperic based on the mechanisms commonly believed to lead to neurocardiogenic fainting. To determine the utility and efficacy of drug therapy and an orthostatic self-training program in the prevention of tilt-induced neurocardiogenic syncope, we investigated 43 consecutive patients who had shown syncope and were induced by head-up tilt test reproducibly, with either traditional medical treatments or orthostatic self-training at home. The initial 19 of 43 patients were treated with either oral propranolol or disopyramide therapies. The remaining 24 patients were treated with an orthostatic self-training program alone. Effects of these therapies on head-up tilt test were reevaluated in all patients. Propranolol prevented syncope in only six (32%) and disopyramide in five (26%) of the 19 patients. There was no significant difference in the effectiveness between them. Syncope was prevented in nine (47%) patients with either propanolol or disopyramide therapy alone, while in the remaining 10 patients it was not. On the other hand, orthostatic self-training program prevented syncope in 22 (92%) of 24 patients. We concluded that orthostatic self-training program is far more effective than traditional drug therapies. Orthostatic self-training is an effective, safe and well accepted therapy in the prevention of tilt-induced neurocardiogenic syncope.
机译：尽管已经提出了多种治疗神经心源性晕厥的药物，但是基于通常被认为导致神经心源性晕厥的机制，治疗在很大程度上是皇帝疗法。为了确定药物治疗和体位自我训练计划在预防倾斜诱发的神经心源性晕厥中的效用和功效，我们调查了43例连续表现出晕厥并通过抬头仰卧试验可诱发的连续患者，采用传统医学方法在家中进行理疗或体位自我训练。最初的43例患者中有19例接受了口服普萘洛尔或二吡酰胺治疗。其余24例患者仅接受立位自我训练程序治疗。所有患者均重新评估了这些疗法对抬头倾斜测试的影响。在19例患者中，普萘洛尔仅预防了6例（32％）的晕厥和5例（26％）的双吡yr胺。它们之间的有效性没有显着差异。单独使用普萘洛尔或二吡喃酰胺治疗的9名患者（47％）不能预防晕厥，而其余10例患者则没有。另一方面，体位自我训练程序可以防止24名患者中的22名（92％）发生晕厥。我们得出的结论是，直立性自我训练计划比传统药物疗法有效得多。体位自训练是预防倾斜诱发的神经心源性晕厥的一种有效，安全且广为接受的疗法。

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