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首页> 外文期刊>Journal of Surgical Oncology >Calcium phosphate cement in musculoskeletal tumor surgery.
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Calcium phosphate cement in musculoskeletal tumor surgery.

机译：磷酸钙骨水泥在肌肉骨骼肿瘤手术中的应用。

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BACKGROUND AND OBJECTIVES: Calcium phosphate cement (CPC) is an injectable biocompatible bone substitute that has been used for various applications in orthopedic surgery. However, no extensive clinical studies of the use of CPC to fill bone cavities after curettage of musculoskeletal tumors have been reported. The present study reviewed the results for 56 musculoskeletal tumors treated by curettage and CPC implantation. METHODS: Assessment was based on clinical examination and radiographic findings. Variables for clinical assessment included pain, limb function, and complications. Median follow-up was 18.5 months (range 6-47 months). RESULTS: One patient experienced post-operative fractures. Three patients displayed local recurrence. One patient developed post-operative superficial wound infection, and two patients with large bony defect exhibited non-infectious serous discharge. No serious adverse effects such as deep venous thrombosis, pulmonary embolism were encountered. In all cases, CPC was radiographically well adapted to the surrounding host bone as of final follow-up. CONCLUSIONS: CPC appears to offer a useful bone substitute for the treatment of musculoskeletal tumors. As the follow-up period for this study was short, further long-term follow-up studies are needed.
机译：背景与目的：磷酸钙水泥（CPC）是一种可注射的生物相容性骨替代物，已被用于整形外科手术中的各种应用。但是，尚无关于刮除肌肉骨骼肿瘤后使用CPC填充骨腔的广泛临床研究。本研究回顾了刮除术和CPC植入治疗56例肌肉骨骼肿瘤的结果。方法：评估是基于临床检查和影像学检查结果。临床评估的变量包括疼痛，肢体功能和并发症。中位随访时间为18.5个月（6-47个月）。结果：1例患者发生了术后骨折。三例患者出现局部复发。一名患者术后出现浅表伤口感染，而两名骨缺损较大的患者表现出非感染性浆液性分泌物。没有遇到严重的不良反应，如深静脉血栓形成，肺栓塞。在所有情况下，CPC在最终随访中均在放射学上很好地适应了周围的宿主骨骼。结论：CPC似乎为治疗肌肉骨骼肿瘤提供了有用的骨替代物。由于该研究的随访期很短，因此需要进一步的长期随访研究。

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