BACKGROUND AND OBJECTIVES: Surgical treatment of pelvic chondrosarcoma involving acetabulum is challenging. Primary goals of surgical treatment include local control and prevention of distant metastases. A secondary goal is maintenance of quality of life by avoiding major amputative surgery. The purpose of the study was to review the oncological outcome, functional outcome, and the surgical complications of patients with periacetabular chondrosarcomas in the context of resection and reconstruction treated at one tumor center in the past decade. METHODS: Forty-five cases between June 1998 and June 2007 were retrospectively reviewed. There were 26 men and 19 women with an average age of 41.2 (18-63) years. Patients were followed up for a median time of 37 months (18-119 months). There were 32 patients with conventional chondrosarcomas, 9 with dedifferentiated chondrosarcomas, and 4 with mesenchymal chondrosarcomas. According to Enneking's classification there were: Type II-1, Type I + II-8, Type II + III-23, Type I + II + IV-8, and Type I + II + III-5. Six patients had an external hemipelvectomy, whereas 39 patients underwent a limb-salvage procedure. In 27 patients the defect was reconstructed by a modular hemipelvic endoprosthesis and in 4 patients reconstruction by saddle endoprosthesis. Five patients received reconstruction with devitalized tumor bone and three underwent iliofemoral arthrodesis. RESULTS: The 5-year estimated survival was 62.6%. Local recurrence occurred in 10 (22.2%) patients at an average of 18 months after operations. Ten (22.2%) patients had distant metastasis. The average MSTS 93 score was 68.3% (33.3-100). Eighteen complications occurred in 13 patients (28.9%). Wound complication occurred in six (13.3%) patients. Deep infection rate was 11.1%. CONCLUSIONS: Favorable oncological and functional outcome can be achieved in selected patients with periacetabular chondrosarcomas. The complication rates were still high; however, facing the goal of limb salvage, a certain number of complications is acceptable.
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机译：背景与目的：涉及髋臼的骨盆软骨肉瘤的手术治疗具有挑战性。外科治疗的主要目标包括局部控制和预防远处转移。第二个目标是通过避免大型截肢手术来维持生活质量。这项研究的目的是回顾过去十年来在一个肿瘤中心进行切除和重建的情况下髋臼周围软骨肉瘤患者的肿瘤学结果，功能结果和手术并发症。方法：回顾性分析1998年6月至2007年6月的45例病例。男26例，女19例，平均年龄41.2（18-63）岁。随访患者中位时间37个月（18-119个月）。常规软骨肉瘤32例，去分化软骨肉瘤9例，间充质软骨肉瘤4例。根据Enneking的分类，有：II-1型，I + II-8型，II + III-23型，I + II + IV-8型和I + II + III-5型。 6例患者接受了外部半截骨术，而39例患者接受了肢体挽救手术。 27例患者通过模块化半盆腔内修复术修复了缺损，4例患者通过鞍形修复术进行了修复。 5例患者接受了失活的肿瘤骨再造，3例接受了em股关节固定术。结果：5年估计生存率为62.6％。术后平均18个月，有10例（22.2％）患者发生局部复发。十名（22.2％）患者发生远处转移。 MSTS 93的平均得分是68.3％（33.3-100）。 13例患者发生了18例并发症（28.9％）。六名（13.3％）患者发生了伤口并发症。深层感染率为11.1％。结论：选定的髋臼周围软骨肉瘤患者可取得良好的肿瘤学和功能预后。并发症发生率仍然很高。然而，面对肢体抢救的目标，一定数量的并发症是可以接受的。
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