Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications

Tomaschitz Andreas; Piecha Grzegorz; Ritz Eberhard; Meinitzer Andreas; Haas Josef; Pieske Burkert; Wiecek Andrzej; Rus-Machan Jutta; Toplak Hermann; Maerz Winfried; Verheyen Nicolas; Gaksch Martin; Amrein Karin; Kraigher-Krainer Elisabeth; Fahrleitner-Pammer Astrid; Pilz Stefan

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Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications

机译：Marinobufagenin在原发性高血压和原发性醛固酮增多症中的应用：心力衰竭类固醇具有临床和诊断意义

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Background: The cardiotonic steroid marinobufagenin (MBG) is increasingly suggested to be responsible for some of the cardiovascular injury that has been previously attributed to aldosterone. We examined the clinical correlates of circulating MBG concentrations in hypertensive patients and tested the hypothesis that MBG serves as a reliable diagnostic tool for detecting primary aldosteronism (PA).

机译：背景：强心类固醇marinobufagenin（MBG）越来越多地被认为是先前归因于醛固酮的某些心血管损伤的原因。我们检查了高血压患者循环中MBG浓度的临床相关性，并检验了MBG可以作为检测原发性醛固酮增多症（PA）的可靠诊断工具的假设。

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《Clinical and experimental hypertension: CEH》 |2015年第2期|共8页
作者
Tomaschitz Andreas; Piecha Grzegorz; Ritz Eberhard; Meinitzer Andreas; Haas Josef; Pieske Burkert; Wiecek Andrzej; Rus-Machan Jutta; Toplak Hermann; Maerz Winfried; Verheyen Nicolas; Gaksch Martin; Amrein Karin; Kraigher-Krainer Elisabeth; Fahrleitner-Pammer Astrid; Pilz Stefan;
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词
Aldosterone; cardiovascular; hypertension; marinobufagenin; primary aldosteronism;

机译：醛固酮;心血管;高血压;marinobufagenin;原发性醛固酮增多症;

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1. Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications [J] . Tomaschitz Andreas, Piecha Grzegorz, Ritz Eberhard, Clinical and experimental hypertension: CEH . 2015,第2期

机译：Marinobufagenin在原发性高血压和原发性醛固酮增多症中的应用：心力衰竭类固醇具有临床和诊断意义
2. Comparison of Clinical Features between Primary Aldosteronism and Essential Hypertension in Chinese Patients: A Case-Control Study [J] . Xiaoyu Huang, Shuang Yu, Huangmeng Xiao, International journal of endocrinology . 2021,第a期

机译：患者原发性醛固酮和原发性高血压临床特征的比较：案例对照研究
3. Development of a clinical decision tool to reduce diagnostic testing for primary aldosteronism in patients with difficult-to-control hypertension [J] . Monique E. A. M. van Kleef, Frank L. J. Visseren, Jan Westerink, BMC Endocrine Disorders . 2020,第1期

机译：开发临床决策工具，以减少困难对高血压患者原发性醛固酮症的诊断检测
4. Selectivity Evaluation for Underivatized Steroid Analysis by LC-MS/MS in Clinical Diagnostics [C] . James Bruton, Russell Grant, Brian Rappold American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：LC-MS / MS在临床诊断中的绝经类固醇分析选择性评价
5. Developing an objective traditional Chinese medicine pulse diagnostic model in essential hypertension. [D] . Tang, Chui Yan. 2010

机译：建立原发性高血压的客观中医脉诊模型。
6. The Steroid Content of Adrenal Adenomas and Measurements of Aldosterone Production in Patients with Essential Hypertension and Primary Aldosteronism [O] . Norman M. Kaplan 1967

机译：原发性高血压和原发性醛固酮增多症患者肾上腺腺激素的类固醇含量和醛固酮产生的测定
7. The Steroid Content of Adrenal Adenomas and Measurements of Aldosterone Production in Patients with Essential Hypertension and Primary Aldosteronism* [O] . Kaplan, Norman M. 1967

机译：原发性高血压和原发性醛固酮增多症患者肾上腺腺激素的类固醇含量和醛固酮生成的测定*
8. Study to Determine if Pharmaceutical Cost is Related to Diagnostic Complexity for the Treatment of Essential Hypertension Patients at Womack Army Community Hospital. [R] . Levesque, J. C. 1987

机译：确定药物成本是否与Womack军社社区医院原发性高血压患者诊断复杂性相关的研究。

Marinobufagenin in essential hypertension and primary aldosteronism: a cardiotonic steroid with clinical and diagnostic implications

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