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首页> 外文期刊>癌と化学療法 >Results of local ablation therapy for liver metastases from colorectal cancer using radiofrequency ablation and microwave coagulation therapy (RFA/MCT)
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Results of local ablation therapy for liver metastases from colorectal cancer using radiofrequency ablation and microwave coagulation therapy (RFA/MCT)

机译：射频消融和微波凝固疗法（RFA / MCT）对结直肠癌肝转移进行局部消融治疗的结果

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In addition to hepatectomy and chemotherapy with intra-arterial infusion, local ablation therapy using RFA and MCT has been used for treatment of liver metastases derived from colorectal cancer. We investigated the results of local ablation therapy in such cases conducted at our department. SUBJECTS AND METHODS: This study was conducted in 9 out of 21 patients with liver metastases derived from colorectal cancer, who underwent local ablation therapy with RFA from September 2001. As adjuvant therapy, the divided administration of low-doses CDDP/FU was conducted in all cases. RESULTS: RFA and MCT were used in 9 cases (25 lesions) and in 15 cases (82 lesions), respectively. The three cases of RFA were combined with MCT. The severity of liver metastasis was H1 and H2 in one case each and H3 in seven cases. The tumor diameter was 1.0-4.7 cm (mean, 2.7 cm) and patients underwent cauterization from 1-6 times (mean, 2.4 times). Although there were no critical complications, pyrexia and increased AST/ALT were found. The three-year survival rate was 50%, and thus favorable prognoses were obtained. CONCLUSION: There were no notable complications associated with local ablation therapy for liver metastases derived from colorectal cancer, and this method was thus indicated to be effective for local control in cases in which hepatectomy is impossible.
机译：除了肝切除术和动脉内灌注化疗外，使用RFA和MCT的局部消融治疗还用于治疗大肠癌引起的肝转移。我们在我们的部门调查了这种情况下的局部消融治疗的结果。研究对象和方法：本研究在2001年9月开始接受RFA局部消融治疗的21例大肠癌衍生肝转移患者中，有9例进行了研究。作为辅助治疗，在2011年对低剂量CDDP / FU进行了分次给药所有情况。结果：RFA和MCT分别用于9例（25个病灶）和15例（82个病灶）。 3例RFA合并MCT。肝转移的严重程度分别为H1和H2 1例，H3 7例。肿瘤直径为1.0-4.7厘米（平均2.7厘米），患者接受1-6次电灼（平均2.4倍）。尽管没有严重并发症，但发现发热和AST / ALT升高。三年生存率为50％，因此预后良好。结论：对于大肠癌源性肝转移，局部消融治疗无明显并发症，因此该方法在无法进行肝切除的情况下可有效控制局部。

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