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首页> 外文期刊>癌と化学療法 >Complete response of recurrent gastric cancer to chemotherapy with TS-1 and CPT-11--a case report
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Complete response of recurrent gastric cancer to chemotherapy with TS-1 and CPT-11--a case report

机译:TS-1和CPT-11-对复发性胃癌对化疗的完全反应-病例报告

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摘要

A 58-year-old man with gastric cancer who had undergone distal gastrectomy on February 8, 2001 was revealed to have anorexia, and was diagnosed with a local recurrence in anastomosis by upper GI examination in August 2003. In September 2003, he was given combination chemotherapy with TS-1 50 mg/m2 (days 1-14) and CPT-11 80 mg/m2 (days 1, 8) every 3 weeks. A complete response (CR) was confirmed by endoscopy in December 2003. At present, he has been receiving chemotherapy with only TS-1 50 mg/m2 as a maintenance therapy and continuing CR. However, a trial of combination therapy with TS-1 plus CPT-11 is ongoing, and this combination chemotherapy may well achieve a high response rate. Because the adverse events of this chemotherapy have been mild and tolerable in some of our cases, this regimen is considered very useful.
机译:一名58岁的胃癌患者于2001年2月8日接受了远端胃切除术,被发现患有厌食症,并于2003年8月通过上消化道检查被诊断出吻合口局部复发。2003年9月,他被给予了治疗。每3周一次TS-1 50 mg / m2(第1-14天)和CPT-11 80 mg / m2(第1、8天)的联合化疗。 2003年12月,通过内窥镜检查证实了完全缓解(CR)。目前,他仅接受TS-1 50 mg / m2的化疗作为维持治疗并持续CR。但是,正在进行TS-1加CPT-11联合治疗的试验,这种联合化疗可能会达到很高的缓解率。因为在我们的某些病例中,这种化学疗法的不良事件轻微且可以忍受,所以该方案被认为非常有用。

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