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首页> 外文期刊>感染症学雑誌 >G群に凝集するStreptococcus dysgalactiae subsp.equisimilisによる劇症型溶血レンサ球菌感染症の1例
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G群に凝集するStreptococcus dysgalactiae subsp.equisimilisによる劇症型溶血レンサ球菌感染症の1例

机译:G组聚集的由dysgalactiae的乳链球菌亚种引起的暴发性溶血性Lensasphere感染一例

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Group G streptococcus (GGS) is infrequently associated with severe invasive soft tissue infection and toxic shock syndrome. A 74-year-old woman with a history of lymphedema of the lower extremities after surgical and radiation therapy for uterine cancer and diabetic mellitus and admitted for swelling of the right leg, fever, and dyspnea. She presented with shock and necrotizing cellulitis of the right lower extremity. Laboratory tests showed leukocytepenia, acute renal and liver dysfunction, and muscle damage. She rapidly developed multiple organ failure and necrotizing cellulitis. A swab from skin vesicle, throat, and blood culture grew Group G Streptococcus dysgalactiae subsp. equisimilis. Despite endotoxin hemoadsorption therapy, administration of antibiotics, and intravenous immunoglobulin, she died 9 days after admission due to toxic shock syndrome caused by GGS. The M-protein gene (emm) typing of GGS isolated from both blood and skin lesion showed stG 485.0. Three virulence genes, sagA, slo and skcg, were detected from GGS isolated from them.
机译:G组链球菌(GGS)很少与严重的侵袭性软组织感染和中毒性休克综合征相关。一名74岁的妇女因子宫癌和糖尿病的外科手术和放射疗法而有下肢淋巴水肿史,并因右腿肿胀,发烧和呼吸困难而入院。她患有右下肢的休克和坏死性蜂窝织炎。实验室检查显示白细胞减少,急性肾和肝功能不全以及肌肉损伤。她迅速发展为多器官功能衰竭和坏死性蜂窝织炎。 G组链球菌痢疾半乳杆菌亚种长出了来自皮肤囊泡,咽喉和血液培养的拭子。等值的。尽管进行了内毒素血液吸附疗法,抗生素的施用和静脉内免疫球蛋白治疗,但入院后9天她仍因GGS引起的中毒性休克综合征而死亡。从血液和皮肤病变中分离出的GGS的M蛋白基因(emm)分型显示stG 485.0。从分离自它们的GGS中检测到三个毒力基因sagA,slo和skcg。

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