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Serovars and epidemiological properties of Salmonella isolated from patients with sporadic diarrhea in Yamanashi prefecture during the last 22 years (1985-2006)

机译:最近22年间(1985-2006年)从山梨县零星腹泻患者中分离出的沙门氏菌的血清学和流行病学特征

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摘要

We studied the serovars, yearly and monthly frequency of isolates, and drug susceptibility of 3,028 strains of Salmonella isolated from patients with sporadic diarrhea during April 1985 to December 2006 in Yamanashi Prefecture. Results are as follows : 1) Isolates were serologically classified into 72 different serovars. Predominant serovars were S. Enteritidis (59.3%), S. Typhimurium (10.5%), S. Oranienburg (2.9%), S. Hadar (2.4%), S. Litchfield (2.3%), and S. Infantis (2.0%). 2) Serovars of S. Haifa, S. Schleissheim, S. Livingstone, S. Mikawasima, S. Manhattan, S. Muenchen, S. Emek, S. Dublin, S. Javiana, S. Miami, S. Miyazaki, S. Weltevreden, S. Orion, S. Give, S. Aberdeen, S. Surat and S. Orientalis were isolated from human sources for the first time since 1995 in Yamanashi Prefecture. 3) Yearly frequency of isolation was 305 strains (10.1%) for 1996, 283 strains (9.3%) for 1999, 273 strains (9.0%) for 2000, 238 strains (7.9%) for 1989 and 228 strains (7.5%) for 1997. 4) Monthly frequency of isolation was 567 strains (18.7%) for August, 471 strains (15.6%) for September, 430 strains (14.2%) for July, 340 strains (11.2%) for October and 266 strains (8.8%) for June. 5) Predominant ages of patients from whom Salmonella strains were isolated were 2 years for 199 strains (6.6%), 1 year for 192 strains (6.4%), 3 years for 169 strains (5.6%), 4 years for 161 strains (5.3%), and under 1 year for 110 strains (3.6%). 6) The rate of isolation from males was higher at 56.3% than for females at 43.7%. 7) The isolation frequency of drug-resistant strains was 64.8% in 1985-2006. The most predominant resistance pattern was SM single resistance because of the increase in S. Enteritidis. 8) The number of resistant strains of was 1,435 of 1,780 strains (80.6%) for S. Enteritidis, and 214 of 322 strains (66.5%) for S. Typhimurium, 1 of 87 strains (1.1%) for S. Oranienburg and 73 of 73 strains (100%) for S. Hadar. 9) The serovar S. Typhimurium had much multiple drug resistance strains, being resistant ever to fluoroquinolone.
机译:我们研究了1985年4月至2006年12月在山梨县从散发性腹泻患者中分离出的3,028株沙门氏菌的血清型,分离株的年度和每月频率以及药物敏感性。结果如下:1)根据血清学将分离物分为72种不同的血清型。血清抗体主要为肠炎沙门氏菌(59.3%),鼠伤寒沙门氏菌(10.5%),奥拉宁堡沙门氏菌(2.9%),哈达尔(2.4%),里奇菲尔德(2.3%)和沙门氏菌(2.0%) )。 2)S. Haifa,S。Schleissheim,S。Livingstone,S。Mikawasima,S。Manhattan,S。Muenchen,S。Emek,S。Dublin,S。Javiana,S.Miami,S。Miyazaki,S。自1995年以来,山梨县首次从人类来源中分离出Weltevreden,S。Orion,S。Give,S。Aberdeen,S。Surat和S.Orientalis。 3)1996年的隔离频率为305株(10.1%),1999年为283株(9.3%),2000年为273株(9.0%),1989年为238株(7.9%),228株(7.5%) 1997. 4)8月份的每月分离频率为567株(18.7%),9月份的每月分离频率为471株(15.6%),7月份为430株(14.2%),10月份为340株(11.2%),266株(8.8%) )。 5)分离沙门氏菌菌株的患者的主要年龄为199株(6.6%)为2年,192株(6.4%)为1年,169株(5.6%)为3年,161株(5.3为5.3) %),并在1年内处理了110株(3.6%)。 6)与男性的隔离率是56.3%,高于女性的43.7%。 7)1985-2006年耐药菌株的分离频率为64.8%。由于肠炎沙门氏菌的增加,最主要的电阻模式是SM单电阻。 8)肠炎链球菌1780株(80.6%)中的1435株,鼠伤寒沙门氏菌322株(66.5%)中的214株,奥拉宁堡S.的87株(1.1%)中的1株和73株。 S. Hadar的73个菌株(100%)。 9)鼠伤寒沙门氏菌具有多种耐药菌株,对氟喹诺酮类耐药。

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