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An analysis of the 2002-2003 influenza epidemic focusing on patients infected with types A and B in the same season sequentially

机译:对2002-2003年流感流行进行的分析,重点针对同一季节依次感染A型和B型患者

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A total of 2,320 cases of influenza A (1,517 cases) and B (803 cases) in the 2002-2003 influenza season were analyzed. Influenza infection was confirmed by a rapid diagnosis kit, based on the immunochromatography method, at 24 clinics in 18 of the 47 prefectures of Japan. Influenza A/H3N2 was reported between November 22 and April 12 (the median at January 21), and influenza B was reported between December 24 and April 20 (the median at February 16). The mean age of type B patients (16.7 years old) was significantly younger than that of type A patients (26.7 years old) (p < 0.001). Pneumonia was more frequently a complication of type A (0.63%) than of type B (0%, p < 0.05). Although 5 type A patients needed hospitalization, neither hospitalization nor death was associated with type B. Of the 2,293 cases, 27 (1.2%) were infected with both influenza of A and B. The age of these 27 patients ranged from 2 to 51 years (mean of 11.2 years), but 20 of the 27 patients were 9 years of age or under. Type B followed type A in 25 patients. The median date of these 25 type A patients was January 22, similar to that of all cases of type A, January 21. However, the median date of type B infection was March 3, 15 days later than that of all patients with type B, February 16. The mean age of the 27 cases was significantly younger than that of all cases of type A (p < 0.001) and type B (p < 0.05). In epidemics consisting of multiple types of influenza viruses, patients may be infected by more than one virus. This is especially true for children.
机译:分析了2002-2003年流感季节总共2,320例甲型流感(1,517例)和乙型流感(803例)。在日本47个县中的18个县的24个诊所中,通过基于免疫色谱法的快速诊断试剂盒确认了流感感染。在11月22日至4月12日之间报告了A / H3N2流感(中位数为1月21日),在12月24日至4月20日之间报告了B型流感(中位数为2月16日)。 B型患者的平均年龄(16.7岁)比A型患者的平均年龄(26.7岁)显着年轻(p <0.001)。肺炎是A型并发症(0.63%),而不是B型并发症(0%,p <0.05)。尽管有5名A型患者需要住院治疗,但B型患者既没有住院也没有死亡。在2,293例病例中,有27例(1.2%)同时感染了A型和B型流感。这27名患者的年龄在2至51岁之间(平均11.2岁),但27名患者中有20名年龄在9岁以下。在25例患者中,B型紧随A型。这25名A型患者的中位数日期是1月22日,与所有A型病例的1月21日相似。但是,B型感染的中位数日期是3月3日,比所有B型患者晚15天。 ,2月16日。这27例患者的平均年龄显着低于所有A型(p <0.001)和B型(p <0.05)病例。在由多种流感病毒组成的流行病中,患者可能被一种以上的病毒感染。对于儿童尤其如此。

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