...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>臨床病理 >Plasma levels of soluble fibrin in patients with disseminated intravascular coagulation
【24h】

Plasma levels of soluble fibrin in patients with disseminated intravascular coagulation

机译：弥散性血管内凝血患者血浆可溶性纤维蛋白水平

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Soluble fibrin(SF) is formed in the early-activated state of blood coagulation and quantitative measurement of SF shows high potential as a parameter for the diagnosis of suspected disseminated intravascular coagulation(DIC). The aim of the present study is to evaluate the usefulness of a newly developed SF test utilizing SF specific monoclonal antibody(F405). Among hemopoietic and non-hemopoietic tumor patients, 249 patients with suspected DIC were collected. The SF level showed a good correlation with the DIC score and the SF levels in DIC patients were significantly higher than those in s-DIC and pre-DIC patients. Receiver operating characteristic(ROC) analysis also showed that the specificity and sensitivity of the SF assay were higher than those of thrombin-antithrombin complex(TAT). In conclusion, these results indicate that the SF assay is a highly precise method for the diagnosis and screening of DIC stages.
机译：可溶性纤维蛋白（SF）在血液的早期活化状态下形成，对SF的定量测量显示出很高的潜力，可作为诊断可疑弥散性血管内凝血（DIC）的参数。本研究的目的是评估利用SF特异性单克隆抗体（F405）进行的新开发的SF检测的有用性。在造血和非造血肿瘤患者中，收集了249例疑似DIC的患者。 SF水平与DIC评分显示出良好的相关性，DIC患者的SF水平明显高于s-DIC和pre-DIC患者。接受者操作特征（ROC）分析还表明，SF测定的特异性和灵敏度均高于凝血酶-抗凝血酶复合物（TAT）。总之，这些结果表明，SF分析是诊断和筛选DIC阶段的高精度方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号