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Transmission, diagnosis, and recommendations for control of Pseudoloma neurophilia infections in laboratory zebrafish (Danio rerio) facilities.

机译:在实验室斑马鱼( Danio rerio )设施中传播,诊断和建议控制神经假单胞菌感染。

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摘要

The microsporidium Pseudoloma neurophilia represents a considerable challenge for laboratory zebrafish (Danio rerio) facilities. In 2010, P. neurophilia infections were diagnosed in zebrafish from 74% of the facilities that submitted fish to the Zebrafish International Resource Center (ZIRC) pathology service, and this organism remains the most commonly diagnosed pathogen in submitted fish. Accordingly, many of the ZIRC pathology service consultations deal with control and prevention of microsporidiosis. Here we describe observations and experiments performed at the ZIRC elucidating aspects of P. neurophilia transmission in zebrafish colonies. We then review current knowledge about P. neurophilia transmission and diagnosis. Considering this information, we present recommendations for control of P. neurophilia in zebrafish facilities.
机译:微孢子虫神经假单胞菌对实验室斑马鱼(Danio rerio)设施构成了巨大挑战。 2010年, P。在向斑马鱼国际资源中心(ZIRC)病理服务提交鱼的设施中,有74%在斑马鱼中诊断出了嗜神经性感染,这种生物仍然是提交鱼中最常被诊断的病原体。因此,许多ZIRC病理服务咨询都涉及控制和预防小孢子虫病。在这里,我们描述了在ZIRC进行的观察和实验,阐明了P的各个方面。斑马鱼菌落中神经毒症的传播。然后,我们回顾有关 P的当前知识。神经性疾病的传播和诊断。考虑到这些信息,我们提出了控制 P的建议。斑马鱼设施中的神经毒症

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