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首页> 外文期刊>Comparative Medicine >Postanesthesia death and suspected peracute endotoxic shock due to Pseudomonas putida in a cynomolgous macaque (Macaca fascicularis)
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Postanesthesia death and suspected peracute endotoxic shock due to Pseudomonas putida in a cynomolgous macaque (Macaca fascicularis)

机译：食蟹猕猴（Macaca fascicularis）中恶臭假单胞菌导致的麻醉后死亡和怀疑的急性内毒素休克

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An adult male cynomolgous macaque (Macaca fascicularis) died suddenly after anesthesia for a positron emission tomography scan. Bacteriologic culture of the mucopurulent secretions recovered from the endotracheal tube yielded heavy growth of Pseudomonas putida, a known endotoxin producer. Histologically, the lungs had severe, diffuse perivascular edema and neutrophils marginating to the endothelium. The sudden death and the pathologic findings were consistent with peracute endotoxic shock. Numerous environmental swab specimens of the surgical suite and equipment were submitted for bacteriologic culture, as were swab specimens of endotracheal secretions from a control animal; however, Pseudomonas putida was not isolated from any specimen. The animal in this report may have carried Pseudomonas putida as a commensal in the oropharynx, and the stress of anesthesia may have resulted in increased sensitivity to the endotoxin.
机译：成年雄性食蟹猕猴（Macaca fascicularis）在麻醉后突然死亡，进行正电子发射断层扫描。从气管内导管回收的粘液尿分泌物的细菌学培养产生了恶臭假单胞菌的大量生长，恶臭假单胞菌是已知的内毒素生产者。从组织学上看，肺部有严重的弥散性血管周围水肿和嗜中性粒细胞边缘到内皮。猝死和病理结果与急性内毒素性休克一致。外科手术室和设备的许多环境拭子标本和对照动物的气管内分泌物拭子标本都已进行细菌培养。但是，恶臭假单胞菌并未从任何标本中分离出来。本报告中的动物可能在口咽部携带了恶臭假单胞菌作为共鸣，麻醉压力可能导致对内毒素的敏感性增加。

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