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首页> 外文期刊>Comparative Medicine >Adenocarcinoma of the Ileocolic Junction and Multifocal Hepatic Sarcomas in an Aged Rhesus Macaque (Macaca mulatto)
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Adenocarcinoma of the Ileocolic Junction and Multifocal Hepatic Sarcomas in an Aged Rhesus Macaque (Macaca mulatto)

机译：猕猴（猕猴）的回盲交界处和多灶性肝肉瘤的腺癌。

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An aged male rhesus macaque in our colony had decreased appetite and a loss of interest in behavioral testing. CBC analysis revealed a regenerative, microcytic, hypochromic anemia with thrombocytosis, consistent with iron deficiency. A fecal occult blood test was positive. Ultrasound imaging revealed numerous, vascularized focal liver lesions that suggested metastases. The macaque's appetite continued to decrease, and he became more lethargic. At this point, the investigator elected to euthanize themacaque. At necropsy, the ileocolic junction was white and abnormally thickened, and the liver was pale tan with approximately 18 discrete white masses randomly scattered throughout the hepatic parenchyma. Histologically, the mass at the ileocolic junction was identified as an intestinal adenocarcinoma, whereas the liver masses were confirmed to be undifferentiated hepatic sarcomas. This case report describes a rhesus macaque that had 2 unrelated primary neoplasms. A review of the literature indicates that this rhesus macaque is the first reported to have an adenocarcinoma of the ileocolic junction and multiple hepatic sarcomas simultaneously.
机译：我们殖民地中的一头雄性恒河猴猕猴食欲下降，对行为测试的兴趣下降。 CBC分析显示，伴有铁缺乏症的再生性，微细胞性，变色性贫血伴血小板增多。粪便潜血测试呈阳性。超声成像显示大量血管化的局灶性肝病灶提示转移。猕猴的食欲持续下降，他变得昏昏欲睡。在这一点上，研究者选择对他们安乐死。尸检时，回结肠连接处呈白色并异常增厚，肝脏呈棕褐色，有约18个离散的白色肿块，随机散布在整个肝实质中。从组织学上看，在回盲连接处的肿块被鉴定为肠腺癌，而肝脏肿块被确认为未分化的肝肉瘤。该病例报告描述了具有2个无关的原发性肿瘤的恒河猴。文献综述表明，该恒河猴是第一个同时患有回盲结和多个肝肉瘤的腺癌。

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