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首页> 外文期刊>Comparative Medicine >Interstitial myocardial fibrosis in a captive chimpanzee (Pan troglodytes) population.
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Interstitial myocardial fibrosis in a captive chimpanzee (Pan troglodytes) population.

机译：圈养黑猩猩（Pan穴居人）人群的间质性心肌纤维化。

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摘要

The clinical and necropsy records of 36 (25 male and 11 female) chimpanzees age 10 to 40 y old that died over a 6-y period (2001 to 2006) were reviewed. All animals had annual physical exams that included electrocardiograms and serial blood pressures. Nine of the 36 animals had a complete cardiac evaluation by a board certified veterinary cardiologist, and 7 of the 36 animals (19%) were diagnosed with some form of cardiomyopathy. Systemic hypertension was noted in 3 cases. Cardiac arrhythmias (ventricular ectopy) were seen in 15 (12 male and 3 female) of the 36 animals (42%). Sudden cardiac death (SCD) occurred in 13 (11 male and 2 female) chimps (36%) and was the leading cause of death (n = 13), followed by renal failure (n = 9) and septicemia (n = 3). Histologic examination of the hearts revealed interstitial myocardial fibrosis (IMF) in 29 chimpanzees (81%), and all of the animals that died suddenly due to cardiac causes had IMF to varying degrees. More data will be needed to identify the possible causes of IMF in captive chimpanzees, and IMF may be associated with arrhythmias and SCD in these animals.
机译：回顾了在6年内（2001年至2006年）死亡的36例（25例男性和11例女性）10至40岁的黑猩猩的临床和尸检记录。所有动物每年都要进行身体检查，其中包括心电图检查和连续血压检查。由委员会认证的兽医心脏病专家对36只动物中的9只进行了完整的心脏评估，并且36只动物中的7只（19％）被诊断出患有某种形式的心肌病。 3例发现全身性高血压。在36只动物中有15只（雄性12例，雌性3例）中发现了心律失常（室性异位）（42％）。突然的心源性死亡（SCD）发生在13例黑猩猩（11例男性和2例女性）（36％）中，是主要的死亡原因（n = 13），其次是肾衰竭（n = 9）和败血病（n = 3）。 。心脏的组织学检查发现29只黑猩猩（81％）出现了间质性心肌纤维化（IMF），并且所有因心脏原因突然死亡的动物都有不同程度的IMF。需要更多的数据来确定圈养黑猩猩中IMF的可能原因，而这些动物中IMF可能与心律不齐和SCD有关。

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