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Standard PREanalytical Codes: A New Paradigm for Environmental Biobanking Sectors Explored in Algal Culture Collections

机译：标准的分析前法规：藻类培养物中探索的环境生物库行业的新范式

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摘要

The Standard PREanalytical Code (SPREC) was developed by the medical/clinical biobanking sector motivated by the need to harmonize biospecimen traceability in preanalytical processes and enable interconnectivity and interoperability between different biobanks, research consortia, and infrastructures. The clinical SPREC (01) consists of standard preanalytical variable options (7-code elements), which comprise published and (ideally) validated methodologies. Although the SPREC has been designed to facilitate clinical research, the concept could have utility in biorepositories and culture collections that service environmental and biodiversity communities. The SPREC paradigm can be applied to different storage regimes across all types of biorepository. The objective of this article is to investigate adapting the code in nonclinical biobanks using algal culture collections and their cryostorage as a case study. The SPREC (01) is recalibrated as a putative code that might be adopted for biobanks holding different types of biodiversity; it is extended to include optional coding from the point of sample collection to post- cryostorage manipulations, with the caveat that the processes are undertaken by biorepository personnel.
机译：标准前分析规范（SPREC）是由医疗/临床生物银行部门制定的，其动机是需要协调分析前过程中生物样本的可追溯性，并实现不同生物库，研究财团和基础设施之间的互连性和互操作性。临床SPREC（01）包括标准的分析前变量选项（7个代码元素），其中包括已发布的（理想的）经过验证的方法。尽管SPREC旨在促进临床研究，但该概念可能会在为环境和生物多样性社区服务的生物资源库和文化馆藏中发挥作用。 SPREC范例可以应用于所有类型的生物存储库中的不同存储方案。本文的目的是使用藻类培养物收集物及其冷冻储库作为案例研究，研究如何在非临床生物库中修改代码。 SPREC（01）被重新校准为可能适用于拥有不同类型生物多样性的生物库的假定代码;从样本采集到冷冻储藏后的操作，它被扩展为包括可选的编码，并告诫过程是由生物存储人员进行的。

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