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首页> 外文期刊>Colon & Rectum >No rectopexy versus rectopexy following rectal mobilization for full-thickness rectal prolapse: a randomized controlled trial
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No rectopexy versus rectopexy following rectal mobilization for full-thickness rectal prolapse: a randomized controlled trial

机译:直肠动员全厚度直肠脱垂后无直肠再狭窄与直肠再狭窄:一项随机对照试验

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摘要

Background: No randomized controlled trial has compared no rectopexy with rectopexy for external full-thickness rectal prolapse. Objective: This study was performed to test the hypothesis that recurrence rates following no rectopexy are not inferior to those following rectopexy for full-thickness rectal prolapse. Design: This was a multicenter randomized controlled trial. Eligible patients were randomly assigned to no rectopexy or rectopexy. The end point was recurrence rates defined as the presence of external full-thickness rectal prolapse after surgery. A prerandomized controlled trial meta-analysis suggested a sample size of 251 patients based on a 15% expected difference in the 5-year cumulative recurrence rate. Recurrence-free curves were generated and compared using the Kaplan-Meier method and log-rank test, respectively. Data were presented as median (range).
机译:背景:目前尚无一项随机对照试验对外部全层直肠脱垂没有进行过直肠癌的患者进行比较。目的:进行这项研究是为了检验以下假设,即无全角膜切除术后的全层直肠脱垂的复发率不低于全角膜切除术后的复发率。设计:这是一个多中心随机对照试验。符合条件的患者被随机分配为无再狭窄或再狭窄。终点是复​​发率,定义为手术后出现外部全层直肠脱垂。一项随机前的对照试验荟萃分析表明,基于5年累积复发率15%的预期差异,样本量为251名患者。分别生成无复发曲线并使用Kaplan-Meier方法和对数秩检验进行比较。数据表示为中位数(范围)。

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