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Public Perception and Attitude of Saudis Toward Organ and Tissue Donation

机译：沙特人对器官和组织捐赠的公众看法和态度

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Biobanks depend on the willingness of people to contribute samples for both research and storage; however, the requirements to perform research on biobanked samples are different than the requirements for their use in organ transplants. The objectives of this study were (1) to characterize public attitudes toward tissue and organ donation for transplantation and biobanking and (2) to identify significant predictors of these attitudes. A cross-sectional study was conducted with a total of 1051 adult subjects, all of whom accompanied their ill relatives to the outpatient clinics at King Abdulaziz Medical City. All subjects were given an interview questionnaire about their previous healthcare experiences and an attitude scale to assess their willingness to participate in organ donation for transplantation or tissue donation for research. A total of 64.7% of all participants reported having a positive attitude toward organ donation, and 68.8% of participants reported having a positive attitude toward biobanking. There was a significant and direct correlation between the attitude score related to organ donation and the attitude score related to tissue donation for research (r=0.513, P<0.001). After adjusting for other variables by multiple regression analyses, a positive attitude toward either organ donation or tissue donation for research was significantly more prevalent among females (P<0.001), those who had previously participated in health-related research (P<0.001 and P=0.002, respectively), and those who were aware of organ retention controversies (P=0.036 and P=0.001, respectively). Other significant predictors of positive attitudes toward only biobanking were a history of previous blood tests (P=0.038) and the completion of secondary education (P<0.001). The attitude of the Saudi public is favorable toward both organ donation and tissue biobanking. Attitudes about the 2 types of donations are related. Previous participation in health-related research and awareness of organ retention controversies are significant predictors of attitudes toward both types of donations.
机译：生物库取决于人们愿意为研究和存储提供样本的意愿。但是，对生物库样品进行研究的要求不同于其在器官移植中使用的要求。这项研究的目的是（1）表征公众对器官和器官捐赠以进行移植和生物存储的态度，以及（2）确定这些态度的重要预测因子。对总共1051名成年受试者进行了横断面研究，所有受试者均将患病的亲属陪同到阿卜杜勒阿齐兹国王医疗城的门诊。所有受试者均接受了关于他们以前的医疗保健经历和态度量表的访谈问卷，以评估他们参与器官捐赠以进行移植或组织捐赠以进行研究的意愿。共有64.7％的参与者表示对器官捐赠持积极态度，而68.8％的参与者表示对生物银行持积极态度。与器官捐赠有关的态度得分与与组织捐赠有关的态度得分之间存在显着且直接的相关性（r = 0.513，P <0.001）。在通过多元回归分析对其他变量进行调整之后，对女性器官捐献或组织捐献进行研究的积极态度在女性中更为普遍（P <0.001），之前曾参与健康相关研究的女性（P <0.001和P = 0.002），以及那些意识到器官保留争议的人（分别为P = 0.036和P = 0.001）。对仅生物库的积极态度的其他重要预测指标是以前的血液检查史（P = 0.038）和中学教育的完成（P <0.001）。沙特公众的态度对器官捐赠和组织生物银行都有利。有关这两种捐赠的态度是相关的。先前参与健康相关研究以及对器官保留争议的认识是对两种捐赠态度的重要预测指标。

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